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New drug cocktail targets tough breast cancer in major trial

NCT ID NCT06790693

Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 04, 2026 · Updated 5 times

Summary

This study tests whether adding the drug inavolisib to standard hormone therapy and a CDK4/6 inhibitor can help people with a specific type of advanced breast cancer (PIK3CA-mutated, HR+, HER2-). About 450 adults whose cancer has not been treated yet in the advanced setting will receive either the new combination or a placebo. The goal is to see if the new combination delays cancer growth and improves survival.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 450 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Feb 2032

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women or men with histologically or cytologically confirmed carcinoma of the breast * Documented ER-positive and/or progesterone receptor-positive tumor according to American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) guidelines * Documented HER2-negative tumor according to ASCO/CAP guidelines * De-novo HR+ , HER2- ABC, or, alternatively, relapsed HR+ , HER2- ABC after at least 2 years of standard neoadjuvant/adjuvant endocrine therapy without disease progression during that treatment and disease-free interval of at least 1 year since the completion of that treatment * Participants who have bilateral breast cancers which are both HR-positive and HER2-negative * Confirmation of biomarker eligibility * Consent to provide fresh or archival tumor tissue specimen * Measurable disease per Response Evaluation Criteria in Solid Tumors, Version 1.1 (RECIST v1.1) * Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1 * Adequate hematologic and organ function within 14 days prior to initiation of study treatment Exclusion Criteria: * Pregnant or breastfeeding, or intention of becoming pregnant during the study or within the time frame in which contraception is required * Metaplastic breast cancer * Any prior systemic therapy for locally advanced unresectable or metastatic breast cancer * Type 2 diabetes requiring ongoing systemic treatment at the time of study entry; or any history of Type 1 diabetes * Any history of leptomeningeal disease or carcinomatous meningitis * Known and untreated, or active CNS metastases. Participants with a history of treated CNS metastases are eligible * Active inflammatory or infectious conditions in either eye or history of idiopathic or autoimmune-associated uveitis in either eye * Symptomatic active lung disease * History of or active inflammatory bowel disease * Any active bowel inflammation * Prior hematopoietic stem cell or bone marrow transplantation * Treatment with strong cytochrome P450 (CYP) 3A4 inhibitors or strong CYP3A4 inducers within 4 weeks or 5 drug-elimination half-lives, prior to initiation of study treatment

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Get notified about this study

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    239 sites in 20 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • A.O. S. Anna e San Sebastiano

    RECRUITING

    Caserta, Campania, 81100, Italy

  • A.O. Santa Maria Terni

    RECRUITING

    Terni, Umbria, 05100, Italy

  • A.O. Universitaria Federico II Di Napoli

    RECRUITING

    Naples, Campania, 80131, Italy

  • A.O. Universitaria Policlinico Di Modena

    RECRUITING

    Modena, Emilia-Romagna, 41100, Italy

  • Abdurrahman Yurtarslan Onkoloji Training and Research Hospital

    RECRUITING

    Ankara, 06200, Turkey (Türkiye)

  • Abraham Oncology

    RECRUITING

    Richards Bay, 3900, South Africa

  • Aichi Cancer Center

    RECRUITING

    Aichi, 464-8681, Japan

  • Ankara City Hospital

    RECRUITING

    Ankara, 06800, Turkey (Türkiye)

  • Antiguo Hospital Civil de Guadalajara Fray Antonio Alcalde

    RECRUITING

    Guadalajara, 44280, Mexico

  • Arthur J.E. Child Comprehensive Cancer Center

    RECRUITING

    Calgary, Alberta, T2N 4C2, Canada

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

  • Asst Papa Giovanni XXIII

    RECRUITING

    Bergamo, Lombardy, 24127, Italy

  • Astera Cancer Care East Brunswick

    RECRUITING

    East Brunswick, New Jersey, 08816, United States

  • Az. Osp. G. Panico

    RECRUITING

    Tricase (LE), Apulia, 73039, Italy

  • Azienda Sanitaria dell'Alto Adige;U.O.C. Oncologia Medic

    RECRUITING

    Bolzano, Trentino-Alto Adige, 39100, Italy

  • Ba?c?lar Medipol Mega Üniversite Hastanesi

    RECRUITING

    Istanbul, 34214, Turkey (Türkiye)

  • Bakirkoy Dr. Sadi Konuk Egitim ve Arastirma Hastanesi, Tibbi Onkoloji

    RECRUITING

    Bakirkoy / Istanbul, 34147, Turkey (Türkiye)

  • Baptist Health Hamburg

    RECRUITING

    Lexington, Kentucky, 40509, United States

  • Baptist Health Lexington

    RECRUITING

    Lexington, Kentucky, 40503, United States

  • Baptist Health Louisville

    RECRUITING

    Louisville, Kentucky, 40207, United States

  • Bialostockie Centrum Onkologii

    RECRUITING

    Bialystok, 15-027, Poland

  • Blackpool Victoria Hospital

    RECRUITING

    Blackpool, FY3 8NR, United Kingdom

  • Blacktown Hospital

    RECRUITING

    Blacktown, New South Wales, 2148, Australia

  • Bon Secours - St. Francis Hospital

    RECRUITING

    Greenville, South Carolina, 29607, United States

  • CHUV

    RECRUITING

    Lausanne, 1011, Switzerland

  • COZL Oddzial Onkologii Klinicznej z pododdzialem Chemioterapii Dziennej

    RECRUITING

    Lublin, 20-090, Poland

  • Cancer & Hematology Centers of Western Michigan

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

  • Cancer Care Specialists of Central Illinois

    RECRUITING

    O'Fallon, Illinois, 62269, United States

  • Cancer Specialists of North Florida - Jacksonville

    RECRUITING

    Jacksonville, Florida, 32207, United States

  • Cancer and Blood Specialty Clinic

    RECRUITING

    Los Alamitos, California, 90720, United States

  • CancerCare Manitoba

    RECRUITING

    Winnipeg, Manitoba, R3E 0V9, Canada

  • Caritas Klinik St. Theresia -Frauenklinik Brustzentrum

    RECRUITING

    Saarbrücken, 66113, Germany

  • Caritas-Krankenhaus St. Josef

    RECRUITING

    Regensburg, 93053, Germany

  • Carle Cancer Center

    RECRUITING

    Urbana, Illinois, 61801, United States

  • Centre CARIO - HPCA

    RECRUITING

    Plérin, 22190, France

  • Centre Cancerologie Grand Montpellier

    RECRUITING

    Montpellier, 34070, France

  • Centre Eugene Marquis

    RECRUITING

    Rennes, 35042, France

  • Centre Henri Becquerel

    RECRUITING

    Rouen, 76038, France

  • Centre Hospitalier de l'Universite de Montreal (CHUM)

    RECRUITING

    Montreal, Quebec, H2X 0C1, Canada

  • Centre Oscar Lambret

    RECRUITING

    Lille, 59020, France

  • Centro Estatal de Cancerologia de Chihuahua

    RECRUITING

    Chihuahua City, 31000, Mexico

  • Centro Médico Fleischer

    RECRUITING

    Capital Federal, C1414, Argentina

  • Centro Oncologico Korben

    RECRUITING

    Caba, C1426AGE, Argentina

  • Centro Oncológico de Excelencia

    RECRUITING

    San Juan, J5400, Argentina

  • Centro de Investigacion Clinica de Oaxaca

    RECRUITING

    Oaxaca City, Oaxaca, 68020, Mexico

  • Centro de Investigacion y Tratamiento Integral del Cancer: CITI Cancer Oaxaca S.A de C.V.

    RECRUITING

    Ciudad de Huajuapan de León, Oaxaca, 69007, Mexico

  • Centro de Oncologia de Alfenas

    RECRUITING

    Alfenas, Minas Gerais, 37130-087, Brazil

  • Chia-Yi Christian Hospital

    RECRUITING

    Chiayi City, 600566, Taiwan

  • Chiba Cancer Center

    RECRUITING

    Chiba, 260-8717, Japan

  • Chu La Miletrie

    RECRUITING

    Poitiers, 86021, France

  • Churchill Hospital - Oxford Cancer & Haematology Centre

    RECRUITING

    Oxford, OX3 7LE, United Kingdom

  • City Of Hope

    RECRUITING

    Long Beach, California, 90813, United States

  • City of Hope - Lennar Foundation Cancer Center

    RECRUITING

    Irvine, California, 92618, United States

  • City of Hope - Phoenix

    RECRUITING

    Goodyear, Arizona, 85338, United States

  • City of Hope® Cancer Center Chicago

    RECRUITING

    Zion, Illinois, 60099, United States

  • Cleveland Clinic Florida

    RECRUITING

    Weston, Florida, 33331, United States

  • Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44915, United States

  • Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda

    RECRUITING

    São Paulo, São Paulo, 01317-001, Brazil

  • Colchester General Hospital

    RECRUITING

    Colchester, Essex, CO4 5JL, United Kingdom

  • Community Clinical Trials

    RECRUITING

    Spring, Texas, 77389, United States

  • Crio - Centro Regional Integrado de Oncologia

    RECRUITING

    Fortaleza, Ceará, 60336-232, Brazil

  • Cross Cancer Institute

    RECRUITING

    Edmonton, Alberta, T6G 1Z2, Canada

  • Disney Family Cancer Center

    RECRUITING

    Burbank, California, 91505, United States

  • Dolno?l?skie Centrum Onkologii

    RECRUITING

    Wroc?aw, 53-413, Poland

  • Dres. Andreas Köhler und Roswitha Fuchs

    RECRUITING

    Langen, 63225, Germany

  • Duke Cancer Institute

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Ellison Medical Institute

    RECRUITING

    Los Angeles, California, 90064, United States

  • Fairview Hospital

    RECRUITING

    Cleveland, Ohio, 44111, United States

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    RECRUITING

    Rome, Lazio, 00168, Italy

  • Fukushima Medical University Hospital

    RECRUITING

    Fukushima, 960-1295, Japan

  • Fundacion Instituto Valenciano de Oncologia (IVO)

    RECRUITING

    Valencia, 46009, Spain

  • Gangnam Severance Hospital

    RECRUITING

    Seoul, 06273, South Korea

  • Guangxi Cancer Hospital of Guangxi Medical University

    RECRUITING

    Nanning, 530021, China

  • Gustave Roussy

    RECRUITING

    Villejuif, 94805, France

  • HCA Midwest Health

    RECRUITING

    Kansas City, Missouri, 64132, United States

  • HOPITAL RENE HUGUENIN- Institut Curie

    RECRUITING

    Saint-Cloud, 92211, France

  • Harbin Medical University Cancer Hospital

    RECRUITING

    Harbin, 150081, China

  • Henry Ford Health System

    RECRUITING

    Detroit, Michigan, 48202, United States

  • Hillcrest Hospital

    RECRUITING

    Mayfield Heights, Ohio, 44124, United States

  • Hiroshima University Hospital

    RECRUITING

    Hiroshima, 734-8551, Japan

  • Hokkaido University Hospital

    RECRUITING

    Hokkaido, 060-8648, Japan

  • Hospital Araujo Jorge

    RECRUITING

    Goiânia, Goiás, 74605-070, Brazil

  • Hospital Clinico Universitario Virgen de la Victoria;Servicio de Oncologia

    RECRUITING

    Málaga, 29011, Spain

  • Hospital Clinico Universitario de Valencia

    RECRUITING

    Valencia, 46010, Spain

  • Hospital General Univ. Gregorio Maranon

    RECRUITING

    Madrid, 28009, Spain

  • Hospital General Universitario de Elche

    RECRUITING

    Elche, Alicante, 03203, Spain

  • Hospital General de Mexico

    RECRUITING

    MexicoCiudad de México, Nuevo León, 6726, Mexico

  • Hospital Privado Centro Medico de Cordoba

    RECRUITING

    Córdoba, 5016, Argentina

  • Hospital Santa Rita de Cassia Vitoria

    RECRUITING

    Vitória, Espírito Santo, 29043-260, Brazil

  • Hospital Universitario 12 De Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Hospital Universitario Clínico San Carlos

    RECRUITING

    Madrid, 28040, Spain

  • Hospital Universitario Infanta Leonor

    RECRUITING

    Madrid, 28031, Spain

  • Hospital Universitario Virgen del Rocio

    RECRUITING

    Seville, 41013, Spain

  • Hospital Universitario de la Princesa

    RECRUITING

    Madrid, 28006, Spain

  • Hospital Zambrano Hellion TecSalud

    RECRUITING

    Monterrey, Nuevo León, Mexico

  • Hospital de Basurto

    RECRUITING

    Bilbao, Vizcaya, 48013, Spain

  • Hospital de Cancer de Barretos

    RECRUITING

    Barretos, São Paulo, 14784-400, Brazil

  • Hospital de Navarra

    RECRUITING

    Pamplona/iruña, Navarre, 31008, Spain

  • Hospital do Cancer de Pernambuco - HCP

    RECRUITING

    Recife, Pernambuco, 50040-000, Brazil

  • Hospital do Câncer de Londrina

    RECRUITING

    Londrina, Paraná, 86015-520, Brazil

  • Humanitas Centro Catanese Di Oncologia

    RECRUITING

    Misterbianco (CT), Sicily, 95045, Italy

  • Hunan Cancer Hospital

    RECRUITING

    Changsha, 410013, China

  • Huntsman Cancer Hospital at the University of Utah

    RECRUITING

    Salt Lake City, Utah, 84113, United States

  • Hôpital du Sacré-Coeur de Montreal

    RECRUITING

    Montreal, Quebec, H4J 1C5, Canada

  • ICO L'Hospitalet

    RECRUITING

    L'Hospitalet de Llobregat, Barcelona, 08908, Spain

  • ICO Paul Papin

    RECRUITING

    Angers, 49055, France

  • INSTITUT CURIE_SITE PARIS - Service d'Oncologie Médicale.

    RECRUITING

    Paris, 75005, France

  • IOB Madrid Institute of Oncology Hospital Beata Maria Ana de Jesus;Unidad Central de Oncología Médica y de Investigación Oncológica

    RECRUITING

    Madrid, 28007, Spain

  • IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola

    RECRUITING

    Meldola, Emilia-Romagna, 47014, Italy

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

  • Ico Rene Gauducheau

    RECRUITING

    Saint-Herblain, 44805, France

  • Iem-Fucam

    RECRUITING

    D.F., 04980, Mexico

  • InVO - Institut für Versorgungsforschung in der Onkologie GbR

    RECRUITING

    Koblenz, 56068, Germany

  • Institut Universitaire de Cancer de Toulouse Oncopole

    RECRUITING

    Toulouse, 31100, France

  • Instituto Nacional De Cancerologia

    RECRUITING

    Distrito Federal, Mexico CITY (federal District), 14000, Mexico

  • Instituto Nacional de Cancer - INCa

    RECRUITING

    Rio de Janeiro, 20560-120, Brazil

  • Instituto de Oncologia de Rosario

    RECRUITING

    Rosario, S2013KZE, Argentina

  • Instituto do Cancer do Estado de Sao Paulo - ICESP

    RECRUITING

    São Paulo, São Paulo, 01246-000, Brazil

  • Instytut "Centrum Zdrowia Matki Polki"

    RECRUITING

    ?ód?, 93-338, Poland

  • Irccs Istituto Nazionale Dei Tumori (Int)

    RECRUITING

    Milan, Lombardy, 20133, Italy

  • Istituto Clinico Humanitas

    RECRUITING

    Rozzano, Lombardy, 20089, Italy

  • Izmir Ataturk Training and Research Hospital

    RECRUITING

    Izmir, 35360, Turkey (Türkiye)

  • JPS Health Network

    RECRUITING

    Fort Worth, Texas, 76104, United States

  • Jewish General Hospital

    RECRUITING

    Montreal, Quebec, H3T 1E2, Canada

  • Jiangmen Central Hospital

    RECRUITING

    Jiangmen, 529030, China

  • Jinhua municipal central hospital

    RECRUITING

    Jinhua, 321083, China

  • Kaiser Permanente - San Marcos

    RECRUITING

    San Marcos, California, 92069, United States

  • Kanagawa Cancer Center

    RECRUITING

    Kanagawa, 241-8515, Japan

  • Kantonsspital Baden Zentrum für Onkologie und Hämatologie

    RECRUITING

    Baden, 5404, Switzerland

  • Klinikum Ernst von Bergmann

    RECRUITING

    Potsdam, 14467, Germany

  • Klinikum Essen-Mitte Ev. Huyssens-Stiftung / Knappschafts GmbH

    RECRUITING

    Essen, 45136, Germany

  • Koo Foundation Sun Yat-Sen Cancer Center

    RECRUITING

    Taipei, 112019, Taiwan

  • Kooperatives Mammazentrum Hamburg Krankenhaus Jerusalem

    RECRUITING

    Hamburg, 20357, Germany

  • Kyungpook National University Chilgok Hospital

    RECRUITING

    Daegu, 41404, South Korea

  • Linksfield Oncology Inc.

    WITHDRAWN

    Johannesburg, 2192, South Africa

  • Luzerner Kantonsspital

    RECRUITING

    Lucerne, 6004, Switzerland

  • Lyell McEwin Hospital

    RECRUITING

    Elizabeth Vale, South Australia, 5112, Australia

  • MRUKMED Lekarz Beata Madej-Mruk i Partner Spolka Partnerska Oddzial nr 1 w Rzeszowie

    RECRUITING

    Rzeszów, 35-021, Poland

  • Maroondah hospital;Oncology clinical trials

    RECRUITING

    Ringwood, Victoria, 3135, Australia

  • Medizinische Hochschule Zentrum Frauenheilkunde Abt.Gynäkologische Onkologie

    RECRUITING

    Hanover, 30625, Germany

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • Mersin City Education and Research Hospital

    RECRUITING

    Mersin, 33240, Turkey (Türkiye)

  • Moffitt Cancer Center-McKinley Campus

    RECRUITING

    Tampa, Florida, 33612, United States

  • Monash Health

    RECRUITING

    Clayton, Victoria, 3168, Australia

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10467, United States

  • Mount Sinai West

    RECRUITING

    New York, New York, 10019, United States

  • Mount Vernon & Watford Hospital Trust

    RECRUITING

    Northwood, HA6 2RN, United Kingdom

  • Narodowy Inst.Onkologii im.Sklodowskiej-Curie Panstw.Inst.Bad

    RECRUITING

    Warsaw, 02-781, Poland

  • National Cancer Center

    RECRUITING

    Goyang-si, 10408, South Korea

  • National Cheng Kung Uni Hospital

    RECRUITING

    Tainan, 704, Taiwan

  • National Taiwan Uni Hospital

    RECRUITING

    Taipei, 100, Taiwan

  • Nationales Centrum für Tumorerkrankungen (NCT)

    RECRUITING

    Heidelberg, 69120, Germany

  • Nebraska Cancer Specialists

    RECRUITING

    Grand Island, Nebraska, 68803, United States

  • Nebraska Cancer Specialists

    RECRUITING

    Omaha, Nebraska, 68130-2042, United States

  • Northwest Georgia Oncology Centers PC - Marietta

    RECRUITING

    Marietta, Georgia, 30060, United States

  • Northwest Medical Specialties

    RECRUITING

    Tacoma, Washington, 98405, United States

  • Novant Health Cancer Institute

    RECRUITING

    Charlotte, North Carolina, 28204, United States

  • Novant Health Cancer Institute

    RECRUITING

    Winston-Salem, North Carolina, 27103, United States

  • Obras Sociais Irma Dulce - Osid

    RECRUITING

    Salvador, Estado de Bahia, 40415-006, Brazil

  • Okayama University Hospital

    RECRUITING

    Okayama, 700-8558, Japan

  • Ospedale Civile - Livorno

    RECRUITING

    Livorno, Tuscany, 57124, Italy

  • Ospedale San Raffaele

    RECRUITING

    Milan, Lombardy, 20132, Italy

  • Palo Alto Medical Foundation Research Center

    RECRUITING

    Palo Alto, California, 94301, United States

  • Palo Alto Medical Foundation Research Center

    RECRUITING

    San Mateo, California, 94401, United States

  • Palo Alto Medical Foundation Research Center

    RECRUITING

    Sunnyvale, California, 94086, United States

  • PanOncology Trials

    RECRUITING

    San Juan, 00935, Puerto Rico

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, 100032, China

  • Policlinico S.Orsola-Malpighi

    RECRUITING

    Bologna, Emilia-Romagna, 40138, Italy

  • Princess Alexandra Hospital

    RECRUITING

    Harlow, CM20 1QX, United Kingdom

  • Providence Oncology and Hematology Cancer Clinic - Westside;Investigation Drug Services Pharmacy

    RECRUITING

    Portland, Oregon, 97225, United States

  • Providence Portland Medical Center

    RECRUITING

    Portland, Oregon, 97213, United States

  • Providence Regional Cancer Partnership

    RECRUITING

    Everett, Washington, 98201-1621, United States

  • Przychodnia Lekarska KOMED, Roman Karaszewski

    RECRUITING

    Konin, 62-500, Poland

  • Royal Free Hospital

    RECRUITING

    London, NW3 2QG, United Kingdom

  • Royal North Shore Hospital

    RECRUITING

    St Leonards, New South Wales, 2065, Australia

  • Saitama Medical University International Medical Center

    RECRUITING

    Saitama, 350-1298, Japan

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

  • Santa Casa de Misericordia de Porto Alegre

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90020-090, Brazil

  • Sault Area Hospital

    RECRUITING

    Sault Ste. Marie, Ontario, P6B 0A8, Canada

  • Scripps Health

    RECRUITING

    La Jolla, California, 92040, United States

  • Seoul National University Bundang Hospital

    RECRUITING

    Seongnam-si, 463-707, South Korea

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • Severance Hospital, Yonsei University Health System

    RECRUITING

    Seoul, 03722, South Korea

  • Shandong Cancer Hospital

    RECRUITING

    Jinan, 250117, China

  • Shantou Center Hospital

    RECRUITING

    Shantou, 515031, China

  • Shanxi Provincial People's Hospital

    RECRUITING

    Xi'an, 710068, China

  • Sichuan Provincial People's Hospital

    RECRUITING

    Chengdu, 610072, China

  • Soon Chun Hyang University Cheonan Hospital

    RECRUITING

    Dongnam-gu, Cheonan-si, 31151, South Korea

  • Springfield Clinic

    RECRUITING

    Springfield, Illinois, 62702, United States

  • St Bartholomew's Hospital

    RECRUITING

    London, EC1M 6BQ, United Kingdom

  • St. Elisabeth Krankenhaus Köln GmbH

    RECRUITING

    Cologne, 50935, Germany

  • St. Joseph's Health Centre

    RECRUITING

    Toronto, Ontario, M6R 1B5, Canada

  • Summit Medical Group

    RECRUITING

    Florham Park, New Jersey, 07932, United States

  • Sun Yat-Sen University Cancer Center - Huangpu Campus

    RECRUITING

    Guangzhou, China

  • Sun yat-sen University Cancer Center

    RECRUITING

    Guangzhou, 510060, China

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

  • Swedish Cancer Institute

    RECRUITING

    Seattle, Washington, 98104, United States

  • Swedish Cancer Institute - Edmonds Campus

    RECRUITING

    Edmonds, Washington, 98026, United States

  • Swedish Cancer Institute - Issaquah

    RECRUITING

    Seattle, Washington, 98104, United States

  • Szpital Miejski Specjalistyczny Narutowicza

    WITHDRAWN

    Krakow, 31-202, Poland

  • Szpital Wojewódzki im. Miko?aja Kopernika

    RECRUITING

    Koszalin, 75-581, Poland

  • Taichung Veterans General Hospital

    RECRUITING

    Taichung, 407219, Taiwan

  • Taipei Veterans General Hospital

    RECRUITING

    Taipei, 112201, Taiwan

  • Tallahassee Memorial HealthCare

    RECRUITING

    Tallahassee, Florida, 32308, United States

  • The Blavatnik Family ? Chelsea Medical Center at Mount Sinai

    RECRUITING

    New York, New York, 10011, United States

  • The Cancer Inst. Hosp. of JFCR

    RECRUITING

    Tokyo, 135-8550, Japan

  • The Dignity Health Cancer Institute

    RECRUITING

    Phoenix, Arizona, 85004, United States

  • The Moncton Hospital

    RECRUITING

    Moncton, New Brunswick, E1C 6Z8, Canada

  • The Ottawa Hospital Cancer Center

    RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

  • The Second Affiliated Hospital of Xi'an Jiao Tong University

    RECRUITING

    Xi'an, 710004, China

  • Tianjin Cancer Hospital

    RECRUITING

    Tianjin, 300000, China

  • Tianjin Cancer hospital Airport hospital

    RECRUITING

    Tianjin, 300300, China

  • Tokai University Hospital

    RECRUITING

    Kanagawa, 259-1193, Japan

  • U.O.C. Oncologia Medica Senologica

    RECRUITING

    Naples, Campania, 80131, Italy

  • UPMC Hillman Cancer Center - Magee-Women?s Hospital

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

  • Unité de Recherche Clinique du CISSS de Laurentides

    RECRUITING

    Saint-Jérôme, Quebec, J7Z 2V4, Canada

  • University of Eastern Piedmont - Maggiore della Carità University Hospital

    RECRUITING

    Novara, Umbria, 28100, Italy

  • University of Kentucky - Markey Cancer Center

    RECRUITING

    Lexington, Kentucky, 40536, United States

  • University of Louisville Hospital

    RECRUITING

    Louisville, Kentucky, 40202, United States

  • University of Maryland

    RECRUITING

    Baltimore, Maryland, 21201, United States

  • University of Minnesota Medical Center

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • Universitätsklinik Tübingen

    RECRUITING

    Tübingen, 72076, Germany

  • Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden

    RECRUITING

    Dresden, 01307, Germany

  • Universitätsklinikum Essen

    RECRUITING

    Essen, 45122, Germany

  • Universitätsklinikum Münster

    RECRUITING

    Münster, 48149, Germany

  • Universitätsklinikum Ulm Am Michelsberg

    RECRUITING

    Ulm, 89075, Germany

  • Universitätsspital Basel

    RECRUITING

    Basel, 4031, Switzerland

  • Vall d'Hebron Institute of Oncology (VHIO), Barcelona

    RECRUITING

    Barcelona, 08035, Spain

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37204, United States

  • Velocity Clinical Research

    RECRUITING

    Annapolis, Maryland, 21401, United States

  • Vencer Oncoclínica - Centro de Pesquisa do Piauí

    RECRUITING

    Teresina, Piauí, 64049-200, Brazil

  • West Cancer Center

    RECRUITING

    Germantown, Tennessee, 38138, United States

  • West China Hospital of Sichuan University

    RECRUITING

    Chengdu, 610041, China

  • Western General Hospital

    RECRUITING

    Edinburgh, EH4 2XU, United Kingdom

  • Weston Park Hospital

    RECRUITING

    Sheffield, S10 2SJ, United Kingdom

  • Wielkopolskie Centrum Onkologii im. Marii Sk?odowskiej-Curie

    RECRUITING

    Późna, 61-866, Poland

  • Wits Clinical Research

    RECRUITING

    Soweto, 2013, South Africa

  • Xiangyang Central Hospital

    RECRUITING

    Xiangyang, Hubei, 441106, China

  • Xinjiang Medical University Cancer Hospital

    RECRUITING

    Ürümqi, 830011, China

  • Yunnan Cancer Hospital

    RECRUITING

    Kunming, 650118, China

  • Zhejiang Cancer Hospital

    RECRUITING

    Hangzhou, 310022, China

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