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In-Clinic polyp removal could replace costly sinus surgery

NCT ID NCT02975310

First seen Jan 07, 2026 · Last updated Jun 23, 2026 · Updated 28 times

Summary

This study compares two ways to treat chronic sinusitis with nasal polyps: a new in-clinic procedure done under local anesthesia versus standard sinus surgery in an operating room. Researchers will enroll 140 adults to see if the in-clinic approach controls symptoms just as well, while being faster, cheaper, and easier to access. If successful, it could become the new standard of care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • McGill University Health Center

    RECRUITING

    Montreal, Quebec, H4A 3J1, Canada

    Contact Email: •••••@•••••

    Contact

  • Ottawa Hospital Research Institute

    RECRUITING

    Ottawa, Ontario, K1Y 1J8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Joseph's Hospital London

    RECRUITING

    London, Ontario, N6A 4V2, Canada

    Contact Email: •••••@•••••

    Contact

  • Vancouver General Hospital

    RECRUITING

    Vancouver, British Columbia, Canada

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

endoscopic polypectomy in clinic (polyp removal using a microdebrider under local anesthesia)

What this could lead to

If it works, this could replace expensive sinus surgery with a cheaper, quicker in-clinic procedure for many patients with nasal polyps.

What could go wrong

This is a mid-stage trial with 140 participants, so results may not apply to everyone. The in-clinic procedure may not control symptoms as well as surgery in the long run.

Conditions

The condition(s) this trial relates to.

nasal cavity polyp sinusitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.