New heart scan method could catch hidden lung pressure earlier
NCT ID NCT06038149
First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times
Summary
This study looks at whether a new computer program called IMPULSE can better detect pulmonary hypertension (high blood pressure in the lungs) using standard heart ultrasound. About 200 adults with unexplained breathlessness or risk factors will be checked. The goal is to see if the new method is more accurate than current guidelines.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2023
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients referred into a UK pulmonary hypertension centre for the first time, determined to be of low/intermediate probability of pulmonary hypertension on routine echocardiogram.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Unexplained breathlessness * Risk factors for Pulmonary arterial hypertension (PAH), chronic thromboembolic pulmonary hypertension (CTEPH) * Unexplained elevation of B-type natriuretic peptide (BNP/proBNP) * Referred for catheterisation. Exclusion Criteria: * ESC / BSE echo high probability of PH * Known or suspected congenital heart disease * Patients unlikely to benefit from management of PH or its underlying causes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Golden Jubilee Hospital
Glasgow, Lanarkshire, G81 4DY, United Kingdom
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Royal Free NHS Foundation Trust
London, NW3 2QG, United Kingdom
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Royal Papworth Hospital
Cambridge, CB2 0AY, United Kingdom
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Royal United Hospital NHS Foundation Trust
Bath, Banes, BA1 3NG, United Kingdom
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Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield, South Yorkshire, S10 2JF, United Kingdom
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Other studies related to the condition(s) this trial covers.
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