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New online tool could help doctors spot hidden cancer risks

NCT ID NCT05079334

Knowledge-focused Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a web-based tool called MeTree that collects family health history to estimate a person's risk for inherited cancer. Over 1,800 adults from three medical centers participated. The goal was to see if the tool helps identify high-risk patients more efficiently than standard clinic methods, and to offer genetic counseling to those who need it.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
MeTree family health history questionnaire
What this could lead to
If successful, this tool could help doctors more easily spot patients who might have inherited cancer risks, leading to earlier genetic counseling and better prevention.
What could go wrong
This study is about testing a process, not a treatment. It may not show big improvements in health outcomes, and results might not apply to all clinics or populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,847 people

The number who actually took part.

Started

Jan 2022

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Anyone over 18 years old, receiving care at our study site (virtual included), and willing/able to use the internet.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Receiving care at sites included in study * Able to read and communicate in English * Willing to use the Internet * Currently enrolled in the patient portal, or willing to enroll (VUMC-specific) Exclusion Criteria: * Non-study site patient * Diagnosed with a terminal illness * Unable to speak/read English * Unable/unwilling to use the Internet * Previous genetic testing and/or counseling from the VUMC Hereditary Cancer Clinic

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Conditions

The condition(s) this trial relates to.

hereditary neoplastic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Comparative effectiveness research Neoplastic syndromes, hereditary

Contacts and locations

Locations

  • Meharry Medical College

    Nashville, Tennessee, 37208, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37212, United States

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