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Blood test may tell if your slipped disc will shrink on its own

NCT ID NCT07367503

Knowledge-focused Sponsor: Çanakkale Onsekiz Mart University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 130 people with lumbar disc herniation (a slipped disc in the lower back) to see if a blood-based immune-inflammatory index could predict whether the disc would shrink without surgery. Researchers compared patients who had surgery to those who received only medical treatment. The goal was to find a simple blood test that helps guide treatment decisions, potentially sparing some patients from unnecessary surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors decide which patients with lumbar disc herniation can avoid surgery and recover with medical treatment alone.
What could go wrong
This is a small, completed observational study, not a treatment trial. The findings may not apply to all patients and need confirmation in larger, more diverse groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

130 people

The number who actually took part.

Started

Jun 2020

Finished

Jan 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Dagnosis of lumbar disc herniation confirmed by magnetic resonance imaging (MRI) * Follow-up at the Department of Neurosurgery between June 1, 2020, and January 30, 2023 * Availability of baseline complete blood count and inflammatory marker data * For the surgical group: Patients who underwent single-level, unilateral lumbar microdiscectomy (LMD) for acute lumbar disc herniation * For the medical treatment group: Patients with single-level, unilateral lumbar disc herniation who did not undergo surgery and demonstrated spontaneous regression during follow-up after medical treatment * For the control group: Individuals without spinal disease who applied to the outpatient clinic with headache complaints and had available routine blood test results Exclusion Criteria: * Previous medical or surgical treatment for lumbar disc pathology * Presence of systemic inflammatory disease * Rheumatic disease * Tumoral or malignant pathology * History of spinal trauma * Active infection at the time of blood sampling * Congenital spinal anomalies * Incomplete clinical, laboratory, or radiological data

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Conditions

The condition(s) this trial relates to.

Inflammation inflammatory disease lumbar disk herniation, susceptibility to

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inflammation Lymphocyte Neurosurgery Neutrophil

Contacts and locations

Locations

  • Çanakkale Onsekiz Mart University

    Çanakkale, Center, 17020, Turkey (Türkiye)

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