Blood test may predict sepsis survival
NCT ID NCT07039227
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether measuring immature platelets in the blood can help predict how septic shock patients will fare. Researchers followed 196 intensive care patients and checked if the immature platelet fraction at admission was linked to death or organ failure at 28 days. The goal is to find a low-cost, routine biomarker to identify high-risk patients early.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If this test proves useful, it could give doctors a cheap, quick way to identify septic patients at higher risk of death or organ failure.
- What could go wrong
- This is a completed observational study, not a treatment trial. The test may not be accurate enough to change patient care, and results may not apply to all sepsis patients.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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196 people
The number who actually took part.
- Started
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Apr 2023
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients admitted to critical care for sepsis or septic shock
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Any adult patient admitted to critical care for sepsis defined by a SOFA score \> or = 2 or an increase of at least 2 points if there was organ dysfunction pre-existing to the infection. * For the inflammatory control group, we will include adult patients who have required extracorporeal circulation for more than 1 hour for cardiac surgery. * Patients who have read and understood the information letter and do not object to participating in the study * Patients affiliated with a social security scheme * Exclusion Criteria: * Patient refusal * Pregnant, parturient, or breastfeeding woman * Person deprived of liberty by an administrative or judicial decision or person placed under judicial protection/guardianship or curatorship * Person who does not understand or speak French * Moribund * Febrile aplasia * Hematological diseases * Decompensated cirrhosis * Ongoing chemotherapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Rouen Hospital
Rouen, 76031, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Chilling fever: can cooling septic shock patients save lives?
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- Bedside eye scans may reveal hidden blood flow problems in septic shock
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