Veterans' skin cancer treatment gets a boost from antidepressant cream
NCT ID NCT06778434
First seen Jan 10, 2026 · Last updated Apr 29, 2026 · Updated 18 times
Summary
This study tests whether adding a cream called imipramine (an antidepressant) to standard light therapy (PDT) can improve treatment of actinic keratosis, a common skin pre-cancer, in 48 U.S. veterans. The goal is to see if imipramine reduces immune system suppression caused by PDT, potentially making the treatment more effective and less painful. Participants will apply imipramine cream to one side of their face or forearm before PDT, and the other side will get a placebo cream for comparison.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Dayton VA Medical Center, Dayton, OH
RECRUITINGDayton, Ohio, 45428, United States
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