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Could a cancer drug tame sickle cell pain?

NCT ID NCT03997903

First seen Feb 01, 2026 · Last updated May 23, 2026 · Updated 18 times

Summary

This early-phase study tested the drug imatinib in 7 adults with sickle cell anemia who have frequent pain crises. Researchers wanted to see if imatinib could reduce sickling of red blood cells and lower pain episodes. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital

    Cincinnati, Ohio, 45229, United States

  • Riley Hospital for Children at IU Health

    Indianapolis, Indiana, 46202, United States

Conditions

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