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Can brain scans predict Alzheimer's before memory fails?

NCT ID NCT01582919

First seen May 17, 2026 · Last updated Jun 23, 2026 · Updated 11 times

Summary

This completed study looked at 304 retired farmers aged 65 and older living in rural France. The goal was to find very early brain scan markers for Alzheimer's disease in people who had no memory complaints. Researchers used MRI and PET scans to measure brain volume and other changes over time. The hope is that these imaging markers could lead to earlier diagnosis, even before symptoms appear.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Groupe Hospitalier Pellegrin - C.H.U. de Bordeaux

    Bordeaux, 33000, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors spot Alzheimer's disease much earlier, before memory problems start, allowing for earlier intervention.

What could go wrong

This is an observational study, not a treatment trial. It may not lead to any direct benefit for participants, and the findings might not apply to the general population.

Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction dementia disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.