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Brain scans may reveal earliest signs of Alzheimer's in retired farmers

NCT ID NCT01582919

Knowledge-focused Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at brain scans of 304 retired farmers aged 65 and older living in rural France. None had memory complaints at the start. Researchers used MRI and PET scans to measure brain areas linked to Alzheimer's, like the hippocampus. The goal was to find very early imaging markers that could help diagnose Alzheimer's before symptoms appear.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors detect Alzheimer's disease much earlier, before memory problems start, using brain scans.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to a practical test or change how patients are diagnosed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

304 people

The number who actually took part.

Started

Sep 2012

Finished

Jun 2015

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * At least 65 years old * Be retired from agricultural profession * live in rural area in Gironde (France) Exclusion Criteria: * Lefthanded * having a dementia (MMSE \< 13) * Having a vascular cerebral accident * Parkinson disease * RMI exclusion criteria * \[18F\]-FDG PET SCAN exclusion criteria * Poor health condition does not allowing transport to neuroimaging service

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction dementia disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alzheimer disease Dementia

Contacts and locations

Locations

  • Groupe Hospitalier Pellegrin - C.H.U. de Bordeaux

    Bordeaux, 33000, France

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Other studies related to the condition(s) this trial covers.