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Scientists test new imaging to see muscle pain clearly

NCT ID NCT06036524

Diagnosis Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 16, 2026 · Updated 5 times

Summary

This study aims to develop new imaging methods to better detect and understand myofascial pain, a common muscle pain condition. Researchers will compare 52 participants—some with myofascial pain and some healthy—using MRI, muscle electrical activity, and fiber-optic imaging. The goal is to find reliable biomarkers that can distinguish between painful and normal muscle tissue.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better tools for diagnosing myofascial pain, making it easier to identify and treat.
What could go wrong
This is an early-stage observational study with only 52 participants, so results may not apply to everyone. The imaging methods are still experimental.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

52 people

The number who actually took part.

Started

Oct 2023

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Healthy Volunteer Inclusion Criteria: 1. Absence of a history of chronic pain in the targeted anatomical location (i.e., neck and shoulder) that had limited activities of daily living or work 2. A numerical current pain index of lower than 0.5 according to initial assessment with visual analog scale 3. Able to understand the goal of the project and give informed consent. Healthy Volunteer Exclusion Criteria: 1. Pregnancy or breastfeeding 2. Contraindication to MRI 3. Previous severe/acute neck or shoulder injury 4. Previous neck or shoulder surgery 5. Neck or shoulder deformities 6. Inability to provide consent. Myofascial Pain Patient Inclusion Criteria: 1. Between the ages of 18 and 80 years old 2. Neck and/or shoulder pain, unilateral or bilateral 3. Duration of symptoms for longer than 4 weeks 4. Pain scale at the active state higher than 4 according to initial assessment with visual analog scale 5. Presence of active trigger point(s) according to palpation and/or presence of taut band Myofascial Pain Patient Exclusion Criteria: 1. Recent history of trauma to the neck (e.g., whiplash) 2. Acute cervical radiculopathy 3. Acute cervical spine pain component or acute cervical spinal pathology Presence of neuromuscular pathologies or inflammatory muscle diseases (e.g., dermatomyositis) 4. Systemic disease with diffuse body pain (e.g., system lupus erythematosus and and thyroid disease) 5. Peripheral neuropathy 6. Cancer-related pain 7. Pregnancy, coagulopathy, fever, general/local infection at the pain site, substance abuse, peripheral neuropathy, or any other diseases that may account for signs and symptoms mimicking myofascial pain 8. Contraindication to MRI.

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Conditions

The condition(s) this trial relates to.

myofascial pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Myofascial pain

Contacts and locations

Locations

  • Washington University

    St Louis, Missouri, 63110, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.