New hope for myelofibrosis patients who Can't take standard treatments
NCT ID NCT07447817
First seen Mar 21, 2026 · Last updated May 23, 2026 · Updated 11 times
Summary
This study tests a combination of two drugs, pacritinib and selinexor, in people with myelofibrosis who have not had prior JAK inhibitor therapy and have low red blood cells (anemia) and low platelets (thrombocytopenia). The goal is to see if the combination can shrink an enlarged spleen and improve symptoms. About 26 adults with intermediate- or high-risk myelofibrosis will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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The University of Kansas Cancer Center-Westwood
Westwood, Kansas, 66205, United States
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Wake Forest Baptist Health Comprehensive Cancer Center
Winston-Salem, North Carolina, 27157, United States
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Conditions
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