New drug combo aims to shrink spleen in myelofibrosis patients who Can't take standard therapy
NCT ID NCT07447817
First seen Mar 21, 2026 · Last updated Apr 29, 2026 · Updated 6 times
Summary
This study tests a combination of two drugs, pacritinib and selinexor, in people with myelofibrosis who have low red blood cell and platelet counts and have not yet received JAK inhibitor therapy. The goal is to see if this combination can safely shrink an enlarged spleen and improve symptoms. About 26 adults with intermediate- or high-risk myelofibrosis will take part.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Locations
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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The University of Kansas Cancer Center-Westwood
Westwood, Kansas, 66205, United States
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Wake Forest Baptist Health Comprehensive Cancer Center
Winston-Salem, North Carolina, 27157, United States
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Conditions
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