New drug IDE849 targets tough lung cancers in early trial
NCT ID NCT07174583
First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 28 times
Summary
This study tests a new drug called IDE849 in people with small cell lung cancer and other tumors that have a specific marker (DLL3). The trial has two parts: first, to find the safest dose and check for side effects, and second, to see if the drug shrinks tumors or slows their growth. About 208 participants will receive IDE849 alone or with other treatments. The goal is to control the disease, not cure it.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cabrini Hospital - Malvern
NOT_YET_RECRUITINGClayton, Victoria, 3168, Australia
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Chris O'Brien Lifehouse
NOT_YET_RECRUITINGCamperdown, New South Wales, 2050, Australia
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Chungbuk National University Hospital
NOT_YET_RECRUITINGCheongju-si, North Chungcheong, 361-711, South Korea
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Columbia University Medical Center - Herbert Irving Pavilion
RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dana-Farber Cancer Institute
NOT_YET_RECRUITINGBoston, Massachusetts, 02215, United States
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Faculdade de Medicina de Sao Jose do Rio Preto-SP - Hospital de Base
NOT_YET_RECRUITINGSão José do Rio Preto, São Paulo, 15090-000, Brazil
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Flinders Private Hospital - Southern Oncology Clinical Research Unit (SOCRU)
NOT_YET_RECRUITINGBedford Park, South Australia, 5042, Australia
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Fort Wayne Medical Oncology and Hematology, Inc. - Fort Wayne North Office
NOT_YET_RECRUITINGFort Wayne, Indiana, 46825-1623, United States
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Hopsital Universitario Virgen Macarena
NOT_YET_RECRUITINGSeville, Sevilla, 41009, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Fundación Jiménez Díaz
NOT_YET_RECRUITINGMadrid, Madrid, 28040, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital de Clínicas de Porto Alegre
NOT_YET_RECRUITINGPorto Alegre, São Paulo, 90570-020, Brazil
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Hospital de Câncer de Barretos - Fundação Pio XII
NOT_YET_RECRUITINGBarretos, São Paulo, 14784-400, Brazil
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Mayo Clinic Hospital - Florida
NOT_YET_RECRUITINGJacksonville, Florida, 32224, United States
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McGill University Health Centre
NOT_YET_RECRUITINGMontreal, Quebec, H4A 3J1, Canada
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NEXT Madrid -Hospital Universitario Quiron Salud Madrid
NOT_YET_RECRUITINGPozuelo de Alarcón, Madrid, 28223, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NEXT Oncology Virginia
RECRUITINGFairfax, Virginia, 22031, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Cancer Center
NOT_YET_RECRUITINGGyeonggi-do, Gyeonggi-do, 10408, South Korea
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Next Brasil (Rede D'Or)
NOT_YET_RECRUITINGSão Paulo, São Paulo, 04543-000, Brazil
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Next Oncology Dallas
RECRUITINGIrving, Texas, 75039, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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OSF HealthCare Cancer Institute
NOT_YET_RECRUITINGPeoria, Illinois, 61637, United States
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Oncology Consultants, PA - Houston
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
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Piedmont Physicians Medical Oncology - Atlanta
NOT_YET_RECRUITINGAtlanta, Georgia, 30318, United States
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Princess Alexandra Hospital
NOT_YET_RECRUITINGWoolloongabba, Queensland, 4102, Australia
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Samsung Medical Center
NOT_YET_RECRUITINGSeoul, Seoul, 06351, South Korea
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Sarah Cannon Research Institute - Oncology Partners
RECRUITINGNashville, Tennessee, 37203, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sarah Cannon Research Institute at Florida Cancer Specialists
NOT_YET_RECRUITINGOrlando, Florida, 32827, United States
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Sarah Cannon Research Institute at HealthONE
RECRUITINGDenver, Colorado, 80218, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-••••
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Seattle Cancer Care Alliance
NOT_YET_RECRUITINGSeattle, Washington, 98109-1023, United States
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Severance Hospital - Yonsei Cancer Center
NOT_YET_RECRUITINGSeoul, Seoul, 120-749, South Korea
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Sidney Kimmel Cancer Center at Thomas Jefferson University
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
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South Texas Accelerated Research Therapeutics Madrid - CIOCC - Universitario Sanchinarro
NOT_YET_RECRUITINGMadrid, Madrid, 28050, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Swedish Cancer Institute
RECRUITINGSeattle, Washington, 98104, United States
Contact Email: •••••@•••••
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The Cancer and Hematology Centers
RECRUITINGGrand Rapids, Michigan, 49546, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The University of Chicago Medical Center - Duchossois Center for Advanced Medicine
NOT_YET_RECRUITINGChicago, Illinois, 60637, United States
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The University of Texas MD Anderson Cancer Center Houston, Texas 77030-4000
NOT_YET_RECRUITINGHouston, Texas, 77030-4000, United States
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Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital
NOT_YET_RECRUITINGBunkyō City, Tokyo-To, 113-8677, Japan
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Trinity Health-IHA Medical Group - Hematology Oncology - Ann Arbor Campus
NOT_YET_RECRUITINGAnn Arbor, Michigan, 48106, United States
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University Health Network (UHN) - Princess Margaret Cancer Centre (Princess Margaret Hospital)
NOT_YET_RECRUITINGToronto, Ontario, M5G 2M9, Canada
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Weill Cornell Medicine - Cutaneous Oncology and Melanoma Program
NOT_YET_RECRUITINGNew York, New York, 10065, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.