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New drug aims to unleash Body's hidden cancer killers

NCT ID NCT04243499

First seen Jan 05, 2026 · Last updated May 24, 2026 · Updated 16 times

Summary

This study tests an experimental drug called ICT01, which tries to activate a special type of immune cell (gamma delta T cells) to fight cancer. It is for people with advanced solid tumors or blood cancers that have not responded to other treatments. The study first finds a safe dose, then checks if the drug, alone or with another immunotherapy (Keytruda), can shrink tumors or stop them from growing.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Banner MD Anderson Cancer Center

    Gilbert, Arizona, 85234, United States

  • CHU Lyon

    Lyon, France

  • CHU Nantes

    Nantes, 44093, France

  • CHU Poitiers

    Poitiers, 86000, France

  • Centre Antoine Lacassagne

    Nice, 06189, France

  • Centre Hospitalier Lyon Sud

    Lyon, 69310, France

  • Centre Lyon Berard

    Lyon, France

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

  • Gustave Roussy

    Paris, France

  • H. Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33612, United States

  • Haut Leveque

    Bordeaux, 33600, France

  • Hospital Universitario HM Sanchinarro

    Madrid, 28050, Spain

  • Institut Bergonie

    Bordeaux, 33000, France

  • Institut Curie

    Paris, 75248, France

  • Institut Jules Bordet

    Brussels, Belgium

  • Institut Paoli-Calmettes

    Marseille, France

  • Institute of Cancer Research

    London, United Kingdom

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • NHS Greater Glasgow and Clyde, Beatson West of Scotland Cancer Centre

    Glasgow, United Kingdom

  • Pitie-Salpetriere

    Paris, 75013, France

  • START Barcelone HM Nou Delfos

    Barcelona, 08023, Spain

  • START Madrid-FJD, Hospital Fundación Jiménez Díaz

    Madrid, 28040, Spain

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • US Oncology Research

    Irving, Texas, 75063, United States

  • University Carl Gustav Carus Clinical Trial Unit

    Dresden, Germany

  • University of Washington

    Seattle, Washington, 98133, United States

  • Vall d'Hebron Instiute of Oncology

    Barcelona, Spain

  • Yale Cancer Center

    New Haven, Connecticut, 06511, United States

  • universitatklinikum Wurburg

    Würzburg, Germany

Conditions

Explore the condition pages connected to this study.