New drug ICT01 aims to rally Body's defenses against tough cancers

NCT ID NCT04243499

First seen Jan 05, 2026 · Last updated May 15, 2026 · Updated 15 times

Summary

This study tests a new drug called ICT01, given alone or with the immunotherapy Keytruda, in people with advanced solid tumors or blood cancers that have come back or not responded to treatment. The goal is to see if ICT01 is safe and can help control the cancer by activating a specific type of immune cell. About 292 participants will take part in this early-phase trial.

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Contacts and locations

Locations

  • Banner MD Anderson Cancer Center

    Gilbert, Arizona, 85234, United States

  • CHU Lyon

    Lyon, France

  • CHU Nantes

    Nantes, 44093, France

  • CHU Poitiers

    Poitiers, 86000, France

  • Centre Antoine Lacassagne

    Nice, 06189, France

  • Centre Hospitalier Lyon Sud

    Lyon, 69310, France

  • Centre Lyon Berard

    Lyon, France

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

  • Gustave Roussy

    Paris, France

  • H. Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33612, United States

  • Haut Leveque

    Bordeaux, 33600, France

  • Hospital Universitario HM Sanchinarro

    Madrid, 28050, Spain

  • Institut Bergonie

    Bordeaux, 33000, France

  • Institut Curie

    Paris, 75248, France

  • Institut Jules Bordet

    Brussels, Belgium

  • Institut Paoli-Calmettes

    Marseille, France

  • Institute of Cancer Research

    London, United Kingdom

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • NHS Greater Glasgow and Clyde, Beatson West of Scotland Cancer Centre

    Glasgow, United Kingdom

  • Pitie-Salpetriere

    Paris, 75013, France

  • START Barcelone HM Nou Delfos

    Barcelona, 08023, Spain

  • START Madrid-FJD, Hospital Fundación Jiménez Díaz

    Madrid, 28040, Spain

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • US Oncology Research

    Irving, Texas, 75063, United States

  • University Carl Gustav Carus Clinical Trial Unit

    Dresden, Germany

  • University of Washington

    Seattle, Washington, 98133, United States

  • Vall d'Hebron Instiute of Oncology

    Barcelona, Spain

  • Yale Cancer Center

    New Haven, Connecticut, 06511, United States

  • universitatklinikum Wurburg

    Würzburg, Germany

Conditions

Explore the condition pages connected to this study.