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New hope for hard-to-treat blood cancers?

NCT ID NCT06656494

First seen Jan 04, 2026 · Last updated May 01, 2026 · Updated 17 times

Summary

This early-stage trial tests a new drug (ICP-248) combined with a standard chemotherapy (azacitidine) in people with acute myeloid leukemia or myelodysplastic syndromes. The goal is to find a safe dose and see if the combo helps control the disease. About 266 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Anhui Provincial Hospita

    RECRUITING

    Hefei, Anhui, 230001, China

    Contact Email: •••••@•••••

  • Guangdong Provincial People's Hospital

    RECRUITING

    Guangzhou, Guangdong, 510030, China

    Contact Email: •••••@•••••

  • Henan Cancer Hospital

    RECRUITING

    Zhengzhou, Henan, 450000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nanfang Hospital Southern Medical University

    RECRUITING

    Guangzhou, Guangdong, 510515, China

    Contact Email: •••••@•••••

  • Peking University People's Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100044, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Perth Hospital

    RECRUITING

    Perth, Western Australia, 6000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shengjing Hospital of China Medical University

    RECRUITING

    Shengyang, Liaoning, 110004, China

    Contact Email: •••••@•••••

  • Sichuan Provincial People's Hospital

    RECRUITING

    Chengdu, Sichuan, 610072, China

    Contact Email: •••••@•••••

  • St Vincent's Hospital

    RECRUITING

    Sydney, New South Wales, 2010, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Chongqing Medical University

    RECRUITING

    Chongqing, Chongqing Municipality, 400042, China

    Contact Email: •••••@•••••

  • The First Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, 330006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Soochow University

    RECRUITING

    Suzhou, Jiangsu, 215006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital, Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310012, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, 130000, China

    Contact Email: •••••@•••••

  • Tianjin People's Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300192, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430000, China

    Contact Email: •••••@•••••

  • Yale University, Yale Cancer Center

    RECRUITING

    New Haven, Connecticut, 06520, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.