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New combo shows promise for untreated mantle cell lymphoma

NCT ID NCT02682641

First seen Apr 01, 2026 · Last updated May 23, 2026 · Updated 5 times

Summary

This study tests a combination of two drugs, ibrutinib and rituximab, in 50 adults with a slow-growing form of mantle cell lymphoma who have not had prior treatment. The main goal is to see how many patients achieve complete remission one year after starting treatment. Researchers will also study the genetic profile of the tumors to better understand the disease and response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital Clínic de Barcelona

    Barcelona, Barcelona, 08036, Spain

  • Hospital Clínico de Valencia

    Valencia, Valencia, Spain

  • Hospital Costa del Sol

    Marbella, Málaga, Spain

  • Hospital General Universitario Santa Lucía

    Cartagena, Murcia, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, Madrid, 28041, Spain

  • Hospital Universitario Clinico de Salamanca

    Salamanca, Spain

  • Hospital Universitario Fundación Alcorcón

    Alcorcón, Madrid, Spain

  • Hospital Universitario Mútua Terrassa

    Terrassa, Barcelona, Spain

  • Hospital Universitario Ramon y Cajal

    Madrid, Madrid, Spain

  • Hospital Universitario Vall d'Hebron

    Barcelona, Barcelona, Spain

  • Hospital Universitario Virgen del Rocio

    Seville, Sevilla, Spain

  • Hospital Universitario de Burgos

    Burgos, Burgos, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, Barcelona, Spain

  • Institut Català d'Oncologia

    Barcelona, Barcelona, Spain

  • MD Anderson Cancer Center

    Madrid, Madrid, Spain

Conditions

Explore the condition pages connected to this study.