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New drug duo shows promise for Tough-to-Treat blood cancer

NCT ID NCT02537613

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 25 times

Summary

This study tests a combination of two drugs, ibrutinib and obinutuzumab, in people with chronic lymphocytic leukemia (CLL) whose cancer has returned or not responded to prior therapy. The main goal is to check the safety of different dosing schedules. About 54 adults with CLL or a related lymphoma are taking part. The approach aims to control the disease, not cure it, and participants may need ongoing treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • University of Rochester Wilmot Cancer Inst.

    Rochester, New York, 14642, United States

Conditions

Explore the condition pages connected to this study.