Promising combo aims for deep remission in younger CLL patients
NCT ID NCT02251548
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 21 times
Summary
This study tests whether adding the targeted drug ibrutinib to standard chemotherapy (FCR) can achieve deep remission in younger adults with untreated chronic lymphocytic leukemia (CLL). About 85 participants will receive the combination and be monitored for minimal residual disease (MRD) in the bone marrow. The goal is to see if this approach can eliminate nearly all cancer cells, potentially leading to longer disease control.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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University of Kansas Cancer Center
Westwood, Kansas, 66205, United States
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University of Miami Sylvester Comprehensive Cancer Center
Coral Gables, Florida, 33146, United States
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University of Miami Sylvester Comprehensive Cancer Center
Deerfield Beach, Florida, 33442, United States
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Unversity of Miami Sylvester Comprehensve Cancer Center
Miami, Florida, 33136, United States
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West Michigan Cancer Center
Kalamazoo, Michigan, 49007, United States
Conditions
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