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New hope for ulcerative colitis: experimental drug IBI112 shows promise in phase 2 trial

NCT ID NCT05377580

First seen Nov 19, 2025 · Last updated May 21, 2026 · Updated 25 times

Summary

This study tested a new drug called IBI112 in 150 people with moderate to severe ulcerative colitis, a chronic bowel disease. The goal was to see if IBI112 could help patients achieve remission (symptom-free period) after 12 weeks of treatment. Participants were randomly assigned to receive either IBI112 or a placebo, and neither they nor their doctors knew which they received. The results will help determine if IBI112 is safe and effective enough to move into larger trials.

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Contacts and locations

Locations

  • First Affiliated Hospital of Sun Yat-sen University

    Guangzhou, Guangdong, 510080, China

Conditions

Explore the condition pages connected to this study.