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Can amino acid supplements fix nutrient absorption in kids with damaged guts?

NCT ID NCT07256028

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at 40 stunted children aged 18–36 months who have environmental enteric dysfunction (EED), a gut condition that impairs nutrient absorption. Researchers will give some children milk with added essential amino acids for 28 days, while others get plain milk. They will use special sugar and isotope tests to measure changes in gut permeability and amino acid absorption. The goal is to understand whether supplementation can improve how these children absorb protein building blocks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Indispensable amino acids (IAAs) added to milk
What this could lead to
If successful, this could show that supplementing milk with essential amino acids improves gut health and nutrient absorption in malnourished children.
What could go wrong
This is a small, early-stage observational study with only 40 children. It measures biological markers, not long-term health outcomes, so real-world benefits remain uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Dec 2025

An estimate. Start dates often move.

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 36 months

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Stunting estimated at least - 2 z score height -for-age * Abnormal intestinal morphology on jejunal biopsy showing features for EED: * mucosal inflammation, * villous blunting * altered barrier integrity Exclusion Criteria: * Celiac disease * Presence of anti-tissue transglutaminase antibodies. * Primary immunodeficiency disorders * Inflammatory bowel disease * Intestinal inflammation food allergy

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • department of Pediatric Hepatology Gastroenterology and Nutrition-P III. Children's hospital of Rabat - the Ibn Sina University Hospital Center

    Rabat, Rabat, 10001, Morocco

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