Can amino acid supplements fix nutrient absorption in kids with damaged guts?
NCT ID NCT07256028
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looks at 40 stunted children aged 18–36 months who have environmental enteric dysfunction (EED), a gut condition that impairs nutrient absorption. Researchers will give some children milk with added essential amino acids for 28 days, while others get plain milk. They will use special sugar and isotope tests to measure changes in gut permeability and amino acid absorption. The goal is to understand whether supplementation can improve how these children absorb protein building blocks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Indispensable amino acids (IAAs) added to milk
- What this could lead to
- If successful, this could show that supplementing milk with essential amino acids improves gut health and nutrient absorption in malnourished children.
- What could go wrong
- This is a small, early-stage observational study with only 40 children. It measures biological markers, not long-term health outcomes, so real-world benefits remain uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 36 months
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Stunting estimated at least - 2 z score height -for-age * Abnormal intestinal morphology on jejunal biopsy showing features for EED: * mucosal inflammation, * villous blunting * altered barrier integrity Exclusion Criteria: * Celiac disease * Presence of anti-tissue transglutaminase antibodies. * Primary immunodeficiency disorders * Inflammatory bowel disease * Intestinal inflammation food allergy
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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department of Pediatric Hepatology Gastroenterology and Nutrition-P III. Children's hospital of Rabat - the Ibn Sina University Hospital Center
Rabat, Rabat, 10001, Morocco
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