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Breathing special air before bypass surgery may shield the heart

NCT ID NCT05354648

Disease control Sponsor: Alexander Averyanov Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether breathing air with low and then high oxygen before heart bypass surgery could help protect the heart from damage. 120 adults scheduled for bypass surgery took part. The approach is drug-free and aims to reduce complications after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

Jun 2015

Finished

Feb 2016

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * the need for coronary artery bypass grafting (CABG) Exclusion Criteria: * age over 75 years * emergency surgery * diabetes mellitus * exacerbation of a chronic disease 1 week before surgery * any oncological disease at the time of the examination

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Hyperoxia Hypoxia ischemia reperfusion injury Myocardial Reperfusion Injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary artery disease Hyperoxia Hypoxia Myocardial reperfusion injury

More trials for these conditions

Other studies related to the condition(s) this trial covers.