Could a mouth injection cure your dry mouth?
NCT ID NCT07309588
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether injections of a solution containing hyaluronic acid and amino acids (Sunecos-200) can relieve dry mouth caused by low saliva production. One hundred adults with dry mouth for at least 3 months will receive either the injections or no treatment. The goal is to see if the treatment improves saliva flow and quality of life, while monitoring for side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Sunecos-200 (non-crosslinked hyaluronic acid and amino acids solution)
- What this could lead to
- If it works, this could offer a new way to ease dry mouth and improve comfort for people with low saliva.
- What could go wrong
- This is an early phase 1/2 trial with only 100 participants, so results may not apply to everyone. The treatment involves injections into the mouth, which may cause pain or side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1/2
Runs two stages together: safety and dose first, then whether the treatment works.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Jan 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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38 to 78 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * subjective feeling of dry mouth caused by a lack of saliva for at least 3 month, * informed consent sing by patient, * other complains including difficulty during eating, speaking or swallowing, taste disorders, trouble wearing dentures, the sensation that the tongue is stuck to the palate, bad breath and insomnia, feeling dry mouth at night, which made it difficult or impossible to sleep. Exclusion Criteria: * smoking, * alkohol drinking, * pregnancy, * breast feeding, * diabetes, * immunosuppressive treatment, * neoplastic diseases, * Sjögren disease, * active inflammation in the oral cavity, * participation in other clinical trial in within the last 3 months, * allergy or hipersensitivity to hyaluronic acid or amino acides, * no planned hospital stay during the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Periodontology and Oral Mucosa Diseases, Poznan University of Medical Sciences
Poznan, Greater Poland Voivodeship, 60-812, Poland
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