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Salt water gargle study for COVID-19 fizzles out early

NCT ID NCT04382131

Symptom relief Sponsor: University of Edinburgh Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether rinsing the nose and gargling with salt water could help people with suspected or confirmed COVID-19 feel better faster. Only 16 adults in the UK took part before the study was stopped early. The goal was to see if this simple home remedy could reduce how long symptoms lasted.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

16 people

The number who actually took part.

Started

Jun 2020

Finished

Oct 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (≥18 years) * Those living within the UK * Those self-isolating at home within 48 hours of the start of the illness with: 1. Clinical symptoms suggestive of COVID-19 (i.e. those who have at least one of the following symptoms: recent onset of (i) new continuous cough and/or (ii) high temperature) and/or (iii) loss of, or change in, sense of smell or taste (anosmia) OR 2. Those with virologically confirmed SARS-CoV-2 infection and clinical symptoms indicative of COVID-19 (as detailed in (a) above). * Provision of informed consent Exclusion Criteria: * Onset of illness\>48 hours * Inability to consent * Pregnancy * Immunosuppression * Inability to perform HSNIG * Those taking part in another interventional medical trial * Those without access to a supply of salt * Those who have had a negative COVID-19 swab result for the present symptoms * Those with suspected/confirmed COVID-19 in whom hospital admission is recommended * Those who do not have access to email/internet * Those living in a household with another person currently participating in this study

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Conditions

The condition(s) this trial relates to.

COVID-19 respiratory tract infectious disorder viral infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID Upper respiratory tract infections VIRUS Virus diseases Virus shedding

Contacts and locations

Locations

  • NHS Lothian

    Edinburgh, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.