Can pressurized oxygen boost stem cell transplant success?
NCT ID NCT03964506
First seen Jun 09, 2026 · Last updated Jun 22, 2026 · Updated 4 times
Summary
This early-phase study tests whether adding hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) to standard stem cell transplant conditioning is safe and helpful. It involves up to 24 adults with certain blood cancers or bone marrow disorders. The goal is to see if the oxygen treatment improves engraftment, reduces mouth sores, and lowers infection risk.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Wilmot Cancer Institute, University of Rochester
RECRUITINGRochester, New York, 14642, United States
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hyperbaric oxygen therapy
What this could lead to
If it works, this could improve stem cell transplant recovery and reduce complications like infections and mouth sores.
What could go wrong
This is a very early, small pilot study (24 people) focused on safety. It may not show clear benefits, and hyperbaric oxygen has risks like ear pain or oxygen toxicity.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.