Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Pressurized oxygen may calm PTSD symptoms

NCT ID NCT03466554

Symptom relief Sponsor: Assaf-Harofeh Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help adults with PTSD from combat or terror. Thirty people who had PTSD for at least 4 years and hadn't improved with standard treatments received 60 daily sessions. Researchers used brain scans and questionnaires to measure changes in symptoms, sleep, and thinking.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber)
What this could lead to
If it works, this could offer a new way to ease PTSD symptoms like nightmares and avoidance, especially for people who haven't improved with standard treatments.
What could go wrong
This was a small early study with only 30 people and no placebo group, so results may not be reliable. HBOT also carries risks like ear pain or oxygen toxicity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Mar 2018

Finished

Sep 2019

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 60 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult onset PTSD, defined by DSM-V criteria, as a result of combat or a terror- related event. * Age 25-60 years, 4-years or more from the traumatic event and failure to improve with at least one line of conventional treatment. Exclusion Criteria: * A history of traumatic brain injury, epilepsy, a brain tumor; skull base fractures or neurosurgery. * Severe substance use disorders a current manic episode, psychotic disorders or serious suicidal ideation at baseline. * Major cognitive deficits * History of HBOT for any reason, prior to study enrollment. * Chest pathology incompatible with pressure changes (including active asthma). * Inner ear disease. * The inability to perform an awake brain MRI test. * Inability to provide informed consent

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PTSD are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PTSD

Contacts and locations

Locations

  • Assaf-Harofeh Medical Center

    Ẕerifin, 70300, Israel

More trials for these conditions

Other studies related to the condition(s) this trial covers.