Oxygen chamber treatment for diabetic kidneys falls short
NCT ID NCT03376282
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) could help people with diabetic kidney disease. The goal was to see if it could improve kidney function and reduce protein in the urine. However, the study was stopped early and only included 7 participants, so no strong conclusions can be drawn.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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7 people
The number who actually took part.
- Started
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Sep 2015
- Finished
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May 2020
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The participants are patients of age 18 years or older, who suffered DKD, defined as eGFR\<60ml/min as estimated using MDRD formula, and albuminuria in the presence of diabetes. Diabetic retinopathy and without any alternative cause for their renal disease. Exclusion Criteria: * Exclusions criteria are chest pathology incompatible with HBOT, inner ear disease, claustrophobia. Smoking is not allowed during the study. Patients with uncontrolled diabetes HBA1C\>7.5, recent AKI (3M) recent cardiovascular or cerebrovascular event (6M) or inability to hold the breath for 20-30 seconds are also excluded.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dialysis Clinic in Asaf Harofhe Medical Center
Ẕerifin, 70300, Israel
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Patient's own kidney cells hold off dialysis?
- 12,000 diabetes records put kidney risk under the microscope
- A simple blood ratio may predict diabetic kidney disease
- Can dialysis filters improve kidney recovery? a data review seeks answers
- Can a Patient's own kidney cells slow kidney disease?
- Can we predict kidney damage in young diabetics before it starts?