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Can pressurized oxygen boost athletic recovery?

NCT ID NCT07659301

Knowledge-focused Sponsor: Université Catholique de Louvain Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether breathing oxygen in a pressurized chamber after a hard bike ride helps competitive cyclists recover and perform better the next day. Healthy male road cyclists aged 18 to 40 who compete at the national level in Belgium are randomly assigned to different oxygen exposure levels or a sham condition. The main goal is to see if a single session of post-exercise hyperbaric oxygen improves next-day endurance performance.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hyperbaric oxygen
What this could lead to
If it works, this could provide evidence for a recovery tool that helps athletes bounce back faster after intense exercise.
What could go wrong
This is a small, early-stage study in a specific group of male cyclists, so results may not apply broadly. The effectiveness of hyperbaric oxygen for recovery remains unproven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Road cyclists competing in Elite 2 (Elite without professional contract) or Under-23 (U23) categories or equivalent \[Participation in national-level Belgian competitions within the previous 12 months. No specific ranking, finishing position, or performance threshold is required.\] * ≥ 2 consecutive years of cycling experience at regional or national level, with structured and periodized training * Cycling-specific training volume ≥ 8 h a week over the preceding 10 weeks * Stable training load in the weeks preceding inclusion, with no major changes due to injury, illness, or abnormal overload * Measured VO₂max ≥ 60 ml/kg/min Exclusion Criteria: * Presence of significant cardiovascular, pulmonary, neurological, ENT, or metabolic disease, including but not limited to: Uncontrolled arterial hypertension (systolic blood pressure ≥ 180 mmHg and/or diastolic blood pressure ≥ 110 mmHg) ; Unstable heart disease or decompensated cardiomyopathy * Contraindications to hyperbaric exposure, including: Untreated pneumothorax, History of spontaneous pneumothorax without medical clearance ; Pulmonary conditions associated with air trapping (e.g. emphysema or bullous lung disease), or abnormal thoracic imaging when indicated ; Recent thoracic surgery * Neurological contraindications, including epilepsy, history of oxygen-induced seizures, or recent seizure activity, and any association with cannabis use * Ear, sinus, or Eustachian tube disorders preventing adequate pressure equalization, including active infection or history of severe barotrauma * Severe claustrophobia incompatible with chamber exposure

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Athletic performance Hyperbaric oxygenation Muscle fatigue Oxidative stress Physical endurance

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Institute of Neuroscience, Université catholique de Louvain

    RECRUITING

    Louvain-la-Neuve, Brabant-Wallon, 1348, Belgium

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