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Oxygen therapy shows promise for aging brains and bodies

NCT ID NCT02790541

Disease control Sponsor: Assaf-Harofeh Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve blood flow, brain function, and physical fitness in healthy adults aged 65 and older. Researchers measured changes in brain blood vessels, cognitive test scores, and exercise capacity over 6 months. The goal was to see if this therapy could counter some effects of aging.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

62 people

The number who actually took part.

Start date

Dec 2016

Finished

Jan 2020

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age≥ 65 years * Capability to sign informed consent. * No cardiac or cerebrovascular ischemia previous events one year prior to inclusion. Exclusion Criteria: * Previous treatment with HBOT for any other reason during the last 3 months prior to inclusion. * Any history of malignancy during the last year prior to inclusion. * Severe cognitive decline (MMSA\<17) * Severe chronic renal failure (GFR \<30) * Uncontrolled diabetes mellitus (HbA1C\>8, fasting glucose\>200) * Immunosuppressant from any reason * Contraindications to perform MRI: claustrophobia, allergy to gadolinium, foreign bodies, pacemaker, etc. * Active Smoking. * Pulmonary diseases such as severe emphysema, moderate-severe obstructive disease. * Medical conditions deemed by the investigator to make the patient ineligible for protocol investigations.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging

Contacts and locations

Locations

  • Asaf Harofeh Medical Center

    Ẕerifin, 70300, Israel

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