Hydroxychloroquine trial for rare vasculitis halted early
NCT ID NCT04316494
First seen May 05, 2026 · Last updated Jun 06, 2026 · Updated 8 times
Summary
This study tested whether hydroxychloroquine, a drug used for lupus and arthritis, could help control ANCA vasculitis—a group of autoimmune diseases that cause blood vessel inflammation. Adults with mild disease activity were randomly assigned to receive hydroxychloroquine or a placebo alongside their usual treatments for one year. The trial was terminated early after enrolling 43 of the planned 76 participants.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cambridge University Hospitals NHS Foundation Trust
Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom
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Cardiff & Vale University Health Board
Cardiff, CF14 4XW, United Kingdom
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Cwm Taf Morgannwg University Health Board
Llantrisant, United Kingdom
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East and North Hertfordshire NHS Trust
Stevenage, Hertfordshire, SG1 4AB, United Kingdom
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Epsom and St Helier University Hospitals NHS Trust
Epsom, United Kingdom
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Guy's and St Thomas' NHS Foundation Trust
London, SE1 9RT, United Kingdom
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Imperial College Healthcare NHS Trust
London, W12 0HS, United Kingdom
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King's College Hospital NHS Foundation Trust
London, SE5 9RS, United Kingdom
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Liverpool University Hospitals NHS Foundation Trust
Liverpool, Merseyside, L9 7AL, United Kingdom
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NHS Highland
Inverness, Inverness-shire, IV2 3JH, United Kingdom
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Oxford University Hospitals NHS Foundation Trust
Oxford, United Kingdom
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Royal Berkshire NHS Foundation Trust
Reading, Berkshire, RG1 5AN, United Kingdom
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Royal United Hospitals Bath NHS Foundation Trust
Bath, Somerset, BA1 3NG, United Kingdom
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South Tyneside and Sunderland NHS Foundation Trust
Sunderland, United Kingdom
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Surrey and Sussex Healthcare NHS Trust
Redhill, Surrey, RH1 5RH, United Kingdom
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Torbay and South Devon NHS Foundation Trust
Torquay, United Kingdom
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University Hospitals Sussex NHS Foundation Trust
Brighton, Sussex, BN2 5BE, United Kingdom
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University Hospitals of Leicester NHS Trust
Leicester, Leicestershire, LE3 9QP, United Kingdom
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.