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New painkiller strategy may help moms recover faster after C-Section

NCT ID NCT06823180

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study tested whether giving a low or high dose of hydromorphone (a morphine-like drug) before the end of a C-section can reduce pain afterward. 105 women were split into three groups: low dose, high dose, or a placebo. Researchers measured pain scores, how soon women could move and breastfeed, and any side effects. The goal is to find the best dose for safer, faster recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hydromorphone hydrochloride
What this could lead to
If it works, this could provide a better way to manage pain after C-section, helping mothers recover faster and breastfeed more easily.
What could go wrong
This is a small, completed Phase 4 trial, so results may not apply to all women. The drug can cause side effects like nausea or drowsiness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

105 people

The number who actually took part.

Started

Mar 2025

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

22 to 45 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Parturients with indications for cesarean section; * American Association of Anesthesiologists (ASA) Grade I - II; * No history of sedative drugs or opioid abuse; * Volunteer to join the study Exclusion Criteria: * People with coagulation disorders; * preoperative use of analgesia, non-steroidal drugs; * Abnormal liver and kidney function; * Postoperative drainage is urgently needed.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jiangxi Provincial People's Hospital

    Nanchang, Jiangxi, 330038, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.