Can exercising at home before lung surgery be as good as going to a clinic?
NCT ID NCT06866717
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a prehabilitation program that combines home and center-based exercise works as well as a center-only program for people about to have lung cancer surgery. 38 adults with non-small cell lung cancer will be randomly assigned to either 15 sessions at the center or 3 center sessions plus 12 home sessions using a stationary bike and app. The main goal is to see if both groups improve their aerobic fitness equally before surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- prehabilitation program (exercise training with cycle ergometer, pulse oximeter, activity tracker, and tablet app)
- What this could lead to
- If it works, this could offer a more flexible, accessible way for lung cancer patients to improve their fitness before surgery, potentially leading to better recovery.
- What could go wrong
- This is a small, early-stage trial with only 38 participants, so results may not apply to everyone. Exercise carries risks like muscle soreness or injury, and the home-based approach may not match the center-based program's effectiveness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 38 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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Nov 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \> 18 years * Patient scheduled to undergo lung resection for the treatment of diagnosed or suspected bronchial cancer * Referred for prehabilitation before lung resection surgery * Patient living at home with another adult present during exercise sessions * Surgery date not established at the time of inclusion in the program, or at least 4 weeks away * Peak oxygen uptake below 20 ml/kg/min * Affiliated with a health insurance system * Able to read and understand the information letter and sign the consent form Non-Inclusion Criteria\*: * Oxygen therapy during exercise * Cardiological contraindication to exercise training * Refusal to participate in a center-based prehabilitation training program * Orthopedic, neurological, vascular, or neuromuscular conditions limiting exercise training on a cycle ergometer * Patient under guardianship or curatorship * Pregnant or breastfeeding women Exclusion Criteria: -Withdrawal of consent \*The eligibility criteria were revised in May 2026 following approval of a protocol amendment by the French Ethics Committee (CPP Île-de-France IV). The former non-inclusion criterion of patients receiving concomitant neoadjuvant chemoradiotherapy was removed to better reflect the study population to current clinical practice, as neoadjuvant treatments are increasingly integrated into the care pathway of patients undergoing thoracic surgery for non-small cell lung cancer and referred for pulmonary prehabilitation. The previous restriction had been too limiting and had slowed recruitment. This amendment was proposed to improve the feasibility of recruitment and to increase the representativeness of the study population, while ensuring the safety of the participants as no additional safety concerns were identified and all other exclusion criteria related to safety were unchanged.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Association ADIR
RECRUITINGRouen, 76000, France
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