New hybrid procedure offers hope for debilitating fast heartbeat
NCT ID NCT05280093
First seen Feb 28, 2026 · Last updated May 20, 2026 · Updated 7 times
Summary
This study tests a new hybrid ablation procedure for people with inappropriate sinus tachycardia (IST), a condition causing a fast heart rate that severely impacts quality of life. The procedure combines epicardial and endocardial ablation to spare the sinus node, aiming to safely reduce heart rate without lifelong medication. The trial enrolls 142 adults who have not responded to or cannot tolerate standard drugs, and will measure success by heart rate control and freedom from major complications.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Amsterdam University Medical Center
Amsterdam, Netherlands
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Baptist Health
Miami, Florida, 33143, United States
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Central Clinic Hospital
Warsaw, Poland
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Intermountain Healthcare
Salt Lake City, Utah, 84111, United States
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Kansas City Cardiac Arrhythmia Research LLC
Overland Park, Kansas, 66211, United States
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Loma Linda University Health
Loma Linda, California, 92354, United States
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Maastricht University Medical Center
Maastricht, Netherlands
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Medstar Washington Hospital Center
Washington D.C., District of Columbia, 20010, United States
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Memorial Health University Medical Center
Savannah, Georgia, 31404, United States
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Northern General Hospital
Sheffield, S5 7AU, United Kingdom
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Saint Alphonsus Regional Medical Center
Boise, Idaho, 83706, United States
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Saint Vincent's Medical Center
Bridgeport, Connecticut, 06606, United States
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San Raffaele Hospital
Milan, Italy
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Sarasota Memorial Hospital
Sarasota, Florida, 34239, United States
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Sequoia Hospital
Redwood City, California, 94062, United States
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St. Bernard
Jonesboro, Arkansas, 72401, United States
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St. Joseph's Hospital / Baycare Health System
Tampa, Florida, 33607, United States
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Stanford University
Redwood City, California, 94063, United States
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Swedish Medical Center
Seattle, Washington, 98122, United States
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Texas Cardiac Arrhythmia Research Foundation
Austin, Texas, 78705, United States
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The Christ Hospital
Cincinnati, Ohio, 45219, United States
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TriHealth, Inc.
Cincinnati, Ohio, 45202, United States
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UZ Brussels
Brussels, Belgium
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University of Florida
Gainesville, Florida, 32610, United States
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Virginia Commonwealth University
Richmond, Virginia, 23219, United States
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157, United States
Conditions
Explore the condition pages connected to this study.