New hybrid heart procedure offers hope for debilitating fast heartbeat

NCT ID NCT05280093

First seen Feb 28, 2026 · Last updated May 08, 2026 · Updated 5 times

Summary

This study tests a new hybrid procedure that combines two types of ablation to treat inappropriate sinus tachycardia (IST), a condition causing a fast heart rate and poor quality of life. The procedure aims to reduce heart rate and improve symptoms in 142 patients who have not responded to or cannot tolerate medications. The main goal is to see if the procedure is safe and effective at controlling heart rate for at least 12 months.

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Contacts and locations

Locations

  • Amsterdam University Medical Center

    Amsterdam, Netherlands

  • Baptist Health

    Miami, Florida, 33143, United States

  • Central Clinic Hospital

    Warsaw, Poland

  • Intermountain Healthcare

    Salt Lake City, Utah, 84111, United States

  • Kansas City Cardiac Arrhythmia Research LLC

    Overland Park, Kansas, 66211, United States

  • Loma Linda University Health

    Loma Linda, California, 92354, United States

  • Maastricht University Medical Center

    Maastricht, Netherlands

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Medstar Washington Hospital Center

    Washington D.C., District of Columbia, 20010, United States

  • Memorial Health University Medical Center

    Savannah, Georgia, 31404, United States

  • Northern General Hospital

    Sheffield, S5 7AU, United Kingdom

  • Saint Alphonsus Regional Medical Center

    Boise, Idaho, 83706, United States

  • Saint Vincent's Medical Center

    Bridgeport, Connecticut, 06606, United States

  • San Raffaele Hospital

    Milan, Italy

  • Sarasota Memorial Hospital

    Sarasota, Florida, 34239, United States

  • Sequoia Hospital

    Redwood City, California, 94062, United States

  • St. Bernard

    Jonesboro, Arkansas, 72401, United States

  • St. Joseph's Hospital / Baycare Health System

    Tampa, Florida, 33607, United States

  • Stanford University

    Redwood City, California, 94063, United States

  • Swedish Medical Center

    Seattle, Washington, 98122, United States

  • Texas Cardiac Arrhythmia Research Foundation

    Austin, Texas, 78705, United States

  • The Christ Hospital

    Cincinnati, Ohio, 45219, United States

  • TriHealth, Inc.

    Cincinnati, Ohio, 45202, United States

  • UZ Brussels

    Brussels, Belgium

  • University of Florida

    Gainesville, Florida, 32610, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23219, United States

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.