New registry to reveal if heart ablation helps POTS and IST patients

NCT ID NCT05107635

Recruiting now Knowledge-focused Sponsor: AtriCure, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This registry will follow 500 people with inappropriate sinus tachycardia (IST) or postural orthostatic tachycardia syndrome (POTS) who have had or will have a heart ablation procedure using AtriCure devices. The goal is to collect real-world data on how safe and effective the procedure is. Participants are enrolled at multiple centers in the US and abroad.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cardiac ablation procedure using AtriCure devices
What this could lead to: If successful, this registry could provide clearer evidence on whether heart ablation is a safe and effective option for people with IST or POTS.
What could go wrong: This is an observational registry, not a controlled trial, so it cannot prove cause and effect. Results may be influenced by differences in patient care or device use across sites.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

postural orthostatic tachycardia syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INAPPROPRIATE SINUS TACHYCARDIA POSTURAL TACHYCARDIA SYNDROME

Contacts and locations

Locations

Central Clinic Hospital
RECRUITING

Warsaw, 02-507, Poland
IRCCS Ospedale San Raffaele
RECRUITING

San Raffaele, Italy
Intermountain Medical Center
RECRUITING

Murray, Utah, 84107, United States
Kansas City Cardiac Arrhythmia Research
RECRUITING

Kansas City, Kansas, 64132, United States
MedStar Health Research Institute
RECRUITING

Hyattsville, Maryland, 20782, United States
Sarasota Memorial Hospital
RECRUITING

Sarasota, Florida, 34239, United States
Sequoia Hospital
RECRUITING

Redwood City, California, 94062, United States
Stanford University
RECRUITING

Palo Alto, California, 94305, United States
Texas Cardiac Arrhythmia Research Foundation
RECRUITING

Austin, Texas, 78705, United States
The Carl & Edyth Lindner Center for Research & Education at The Christ Hospital
RECRUITING

Cincinnati, Ohio, 45219, United States
Universitair Ziekenhuis Brussels
RECRUITING

Brussels, Belgium
University of Florida
RECRUITING

Gainesville, Florida, 32608, United States

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