Can a gel injection replace steroids for carpal tunnel pain?
NCT ID NCT07474714
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether hyaluronic acid injections work as well as standard steroid shots for mild to moderate carpal tunnel syndrome. Sixty adults will receive one type of injection under ultrasound guidance, and researchers will track symptom changes and nerve function for three months. The goal is to find a treatment option that eases symptoms without long-term medication.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Numbness or pain in the Median Nerve (MN) distribution. 2. Nerve conduction studies (NCS) consistent with CTS as per the AANEM guidelines. 3. An MN cross-sectional area (CSA) at the wrist \>12 mm² Exclusion Criteria: 1. Patients with severe symptoms (indication for surgery). 2. Patients who show improvement on medical treatment. 3. Patients with previous surgical or injectional CTS treatment. 4. Coexistence of brachial plexopathy, or thoracic outlet syndrome. 5. Patients with infection at the site of injection.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Minia University Hosopital
Minya, 61111, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Scalpel vs sound waves: two carpal tunnel surgeries go head to head
- Can carpal tunnel surgery restore more than hand function?
- Does nerve healing keep pace with hand recovery after carpal tunnel surgery?
- Retraining the brain to ease carpal tunnel pain: a new approach put to the test
- Can a Two-Session acupuncture treatment match ten sessions for carpal tunnel?