Beauty from within? supplement shows promise for dry skin and lips
NCT ID NCT06774742
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested a daily dietary supplement containing a full range of hyaluronic acids in 130 healthy women aged 40-70 with dry facial skin and lips. Participants took either the supplement or a placebo for 3 months, with follow-up visits to measure skin hydration, lip hydration, and other skin quality markers. The goal was to see if the supplement could improve dryness and whether effects lasted after stopping.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- hyaluronic acid supplement (HAFS)
- What this could lead to
- If it works, this supplement could offer a simple way to improve skin and lip hydration in healthy women with dryness.
- What could go wrong
- This is a small, completed study with no phase designation, so results may not be generalizable. The effect may be modest or no better than placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
130 people
The number who actually took part.
- Started
-
Jan 2025
- Finished
-
Jul 2025
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
40 to 70 years
- Sex
-
Female participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Subject having signed an Informed Consent Form (ICF) before any trial related activity is carried out; 2. Female subject; 3. Subject aged 40 to 70 years inclusive at the time of signing the ICF; 4. Subject with thin and dry lips; 5. Subject with dry skin measured on the cheeks (corneometry \< 50); 6. Female subject of childbearing potential must use one of the reliable methods of contraception during the investigation and agree not to change it during the study; 7. Subject willing and able to follow all the study procedures and restrictions and complete the whole study phase; 8. Subject affiliated to a health social security system (according to French Law). Exclusion Criteria: 1. Female subject who is pregnant or who is breast feeding; 2. Female subject of childbearing potential with positive urine pregnancy test at the study visit (Day 1); 3. Women with a BMI ≤ 17 or ≥ 32 kg/cm²; 4. Subject with any uncontrolled diseases such as diabetes, hypertension, hyperthyroidism or hypothyroidism; 5. Presenting or having a history of eating disorder (e.g. anorexia, food allergy) or gastro-intestinal malabsorption such as celiac disease, Crohn's disease, lactose intolerance; 6. Subject with an history of sleeve or bypass 7. Subject with current participation in any other interventional clinical study, based on interview of the subject; 8. Subject with known or suspected hypersensitivity to any component(s) of the investigational products or to any ingredients of the vehicles (i.e., excipients); 9. Subject with skin abnormalities (e.g., scars, excessive hair, tattooing) or any dermatosis (e.g., psoriasis, eczema, acne vulgaris) on the face which could interfere with the study; 10. Subject having applied any cosmetic product (care cream, lotion, body milk…) or drug on the face (except usual cleansing products) within one week before the study visit (Day 1); 11. Subject impossible to contact in case of emergency; 12. Subject who, in the opinion of the investigator, is unlikely to comply with the Clinical Study Protocol (e.g., alcoholism, drug dependency or psychotic state); 13. Subject who is in an exclusion period in the National Biomedical Research Register of the French Ministry of Health at randomization; 14. Subject who has been deprived of their freedom by administrative or legal decision, or who is under care of a guardian or legal guardianship, or subject hospitalized in a medical or social establishment for any reason.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Lips quality are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CPCAD Hôpital L'Archet 2
Nice, 06200, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Viruses that eat bacteria: can phages quiet a troubled gut?
- Can stem cell exosomes reverse facial aging? new trial aims to find out
- Can a collagen serum turn back the clock on aging skin?
- New buttock tightening injection under study
- New skin injection shows promise for hydration
- New shot promises brighter, less dry skin – but does it work?