Gel from joint treatments may speed wisdom tooth healing
NCT ID NCT07318298
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether applying hyaluronic acid gel into the socket after wisdom tooth removal can reduce pain and improve bone healing. Twenty adults needing both lower wisdom teeth out will have one socket treated with the gel and the other with a plain sponge. Pain is tracked with a simple scale, and bone healing is checked with X-rays and a small biopsy six weeks later.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2024
- Expected to finish
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Apr 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Male and female participants aged 18 to 35 years Presence of bilateral impacted mandibular third molars classified as Pell and Gregory Class II, Position B Classified as American Society of Anesthesiologists (ASA) Physical Status I Absence of active local infection at the surgical site (e.g., no swelling, trismus, hyperthermia) Ability to maintain adequate oral hygiene Ability to understand and provide written informed consent Ability to read and understand Arabic or English Willingness to comply with study procedures and follow-up visits Exclusion Criteria: History of systemic diseases such as diabetes mellitus, hypertension, gastric ulcer, or other significant medical conditions Presence of severe or chronic illness requiring frequent hospitalization Pregnant or breastfeeding individuals History of cognitive or motor impairment that may interfere with study participation Use of anti-inflammatory or analgesic medications within two weeks before surgery Known allergy or hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) Current smoker Use of anticoagulant therapy Any condition that, in the investigator's judgment, may interfere with healing or study outcomes
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Higher specialty training center
RECRUITINGIrbid, 11196, Jordan