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New combo therapy targets Hard-to-Treat cancers

NCT ID NCT06520488

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 34 times

Summary

This study is for people with advanced solid tumors that have a specific genetic mutation called KRAS G12D. The trial tests a new drug, HRS-4642, combined with other anti-cancer medicines to see if it is safe and helps shrink tumors. About 118 adults aged 18 to 75 with good performance status and measurable tumors may join. The goal is to find the best dose and measure how well the combination works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Renji Hospital, Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200127, China

    Contact

Conditions

Explore the condition pages connected to this study.