20,000 volunteers needed to unlock throat cancer early detection
NCT ID NCT07033091
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to find out how many healthy adults over 40 carry high-risk HPV in their mouth, which can lead to oropharyngeal cancer. Researchers will test 20,000 volunteers in the Czech Republic to develop a better screening method. The goal is to identify people at risk earlier and improve testing procedures.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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Mar 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants aged 40 years or older at the time of enrollment. * Individuals who are capable of rinsing the oral cavity by gargling independently. * Signed informed consent for study participation, molecular-genetic testing, and personal data processing. Exclusion Criteria: \- Previously diagnosed head and neck cancer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
5 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CLINIQ Dejvice
RECRUITINGPrague, 160 00, Czechia
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Klinika zubního lékařství Fakultní nemocnice Olomouc
RECRUITINGOlomouc, 77900, Czechia
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Masaryk Memorial Cancer Institute
NOT_YET_RECRUITINGBrno, Czechia
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Stomatologická klinika, Fakultní nemocnice u sv. Anny
RECRUITINGBrno, Czechia
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Stomatologické centrum ARTDENT s.r.o.
RECRUITINGJihlava, 586 01, Czechia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a shorter, targeted radiation course tame throat cancer?
- MRI-Guided tweaks during radiation could spare throat cancer patients from swallowing woes
- Can a more intense radiation schedule outperform Chemo-Radiation for head and neck cancer?
- Can less radiation be safer for throat cancer?
- Could a PET scan spare throat cancer patients from High-Dose radiation?
- Could less be more? trial tests reduced radiation and chemo after surgery for HPV-Linked throat cancer