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Can a simple checklist help childhood cancer survivors avoid hearing and vision loss?

NCT ID NCT05582551

Knowledge-focused Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing a new tool called HPARSS that helps doctors identify childhood cancer survivors at risk for hearing or vision problems. The tool uses a patient's past cancer treatments to flag who needs screening. Researchers will see if this approach leads to more kids getting tested and treated for sensory issues. The study involves 146 survivors aged 7 to 17 who finished cancer therapy at least 6 months ago.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple tool that helps doctors spot childhood cancer survivors who need hearing or vision tests, ensuring they get the right care sooner.
What could go wrong
This is a small, early-stage study focused on testing a process, not a treatment. The tool may not work in other hospitals or for all survivors, and it won't directly improve health without proper follow-up.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 146 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2023

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

7 to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with a diagnosis of pediatric cancer (diagnosis at \<18 years of age) * Treatment including chemotherapy and/or radiation therapy * Completion of all cancer therapy for at least 6 months and less than 2 years * Followed in the Division of Pediatric Hematology/Oncology Program at the Washington University School of Medicine * Current age between 7 and 17 years of age (age where all of the screening tests are both valid and have been successfully performed by our group) * English speaking Exclusion Criteria: * Undergoing active cancer treatment * Patient under the care of the Late Effects Program at St. Louis Children's Hospital * Received previous diagnostic testing or rehabilitative therapy for a secondary deficit eligible for screening. * Parents and/or patient illiteracy * No contact with treatment team in the past two years * In foster care or without a legal guardian

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Conditions

The condition(s) this trial relates to.

childhood malignant neoplasm hearing loss disorder neoplasm peripheral nervous system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Childhood cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • St. Louis Children's Hospital - Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

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