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Kitchen spices put to the test for knee pain relief

NCT ID NCT07571772

Symptom relief Sponsor: Ercan Bakır Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether applying a hot compress with black seed or ginger essential oil to the knees for 7 days could reduce pain and improve satisfaction in people with knee osteoarthritis. 120 adults with moderate knee OA were split into four groups: ginger oil plus heat, black seed oil plus heat, heat only, or routine care. Pain and function were measured before and after the week-long treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Black seed (Nigella sativa) essential oil and ginger (Zingiber officinale) essential oil applied topically with hot compress
What this could lead to
If it works, this could offer a simple, natural home remedy to temporarily ease knee pain and stiffness without medication.
What could go wrong
This is a small, short-term study (7 days) with no blinding for the control group, so results may be influenced by placebo effects. It does not test long-term safety or effectiveness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

May 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18 years or older 2. Physician-diagnosed knee osteoarthritis according to American College of Rheumatology (ACR) criteria 3. Kellgren-Lawrence grade 3 (moderate) osteoarthritis 4. Pain score of 4 or higher on Visual Analog Scale (VAS 0-10) 5. No known allergy to Nigella sativa (black cumin) or Zingiber officinale (ginger) essential oils 6. No open wounds on the knee or foot 7. No previous knee surgery 8. Not receiving any other alternative treatment (e.g., acupuncture, herbal therapy) during the study period 9. Females must not be pregnant Exclusion Criteria: 1. Age under 18 years 2. Kellgren-Lawrence grade 1, 2, or 4 3. VAS pain score below 4 4. Known allergy to the essential oils used 5. Open wound on knee or foot 6. Previous knee surgery 7. Receiving other alternative treatment during the study period 8. Pregnancy or breastfeeding 9. Unwillingness to participate or inability to provide informed consent

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee Pain Personal Satisfaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteoarthritis, knee Pain

Contacts and locations

Locations

  • Ercan Bakır

    Erzurum, Yakutiye, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.