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Could a simple home workout protect eyesight in glaucoma?

NCT ID NCT07733388

Disease control Sponsor: Universiti Sains Malaysia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 29, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This trial investigates whether a 12-week home-based circuit training program can reduce intraocular pressure and improve retinal health in people with glaucoma. Participants are randomly assigned to either the exercise program plus standard care or standard care alone. The study aims to see if regular, moderate exercise at home offers additional benefits for managing glaucoma.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a home-based circuit training program combining aerobic and resistance exercises
What this could lead to
If effective, this exercise program could offer a low-cost, accessible way to help manage glaucoma alongside standard treatment.
What could go wrong
This is a small, early-stage trial. Exercise may not lower eye pressure enough to make a clinical difference, and adherence at home may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 - 70 years old * Known case of POAG, PACG, JOAG, NTG * Phakic without visually significant cataract * Pseudophakic for more than 3 months prior to recruitment * Achieved target IOP * Physically not performing routine exercises Exclusion Criteria: * Bilateral eye visual acuity of less than 6/60 * Bilateral eye visual field defect of less than 10 degrees from fixation * Patient with media opacities that affect the reliability of OCT measurements such as cornea opacity, dense cataract with Lens opacification classification system (LOCS III) of more than grade 2, vitreous haemorrhage * Patient who underwent intraocular surgery (other than uncomplicated cataract surgery), including anti-vascular endothelial growth factor injection within past 6 months * Ocular disease such as cornea ulcer, uveitis, age-related macula degeneration * Physical disabilities such as stroke, limbs amputation * Uncontrolled systemic diseases eg diabetes, hypertension * Morbid Obesity (BMI \> 40) * Dementia or any psychiatric diseases * Smoking

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Conditions

The condition(s) this trial relates to.

glaucoma juvenile open angle glaucoma low tension glaucoma open-angle glaucoma primary angle-closure glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Glaucoma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Universiti Sains Malaysia

    Kubang Kerian, Kelantan, 16150, Malaysia

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