New app aims to quiet phantom limb pain in veterans
NCT ID NCT06106984
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a mobile app that guides veterans through mental exercises to reduce phantom limb pain—pain felt where a leg used to be. About 36 veterans with a below-knee amputation will use the app at home with telehealth support. The goal is to see if the app is easy to use and helps manage pain, with the hope of improving daily life.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 36 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2024
- Expected to finish
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Mar 2029
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a US federal agency other than the NIH.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 89 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Must be a military Veteran * At least 18 years old; * \>1 year since unilateral below knee amputation; * Moderate or severe (NRS score 4 on a 0-10 scale) PLP; * Stable medications over the past 2 weeks; * Willing and able to give informed consent; and * Able to participate in the telehealth study activities with a personal device. Exclusion Criteria: * Unstable medical conditions (e.g., uncontrolled diabetes, heart failure exacerbation); * Unstable mental illness or substance use disorder (e.g., active suicidality or psychosis); and * Unable to give informed consent due to a cognitive impairment. * Fibromyalgia or complex regional pain syndrome-like symptoms
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Minneapolis VA Health Care System, Minneapolis, MN
RECRUITINGMinneapolis, Minnesota, 55417-2309, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Spinal Add-On may ease phantom pain after amputation
- Botox shot may silence stubborn nerve pain in amputees
- Battlefield injuries: new study seeks to predict chronic pain before it starts
- Brain implant that turns on only when pain strikes shows promise
- New study seeks to uncover hidden pain in child amputees
- Can VR ease phantom limb pain after amputation?