Experimental HIV vaccine shows promise in early safety trial
NCT ID NCT05781542
First seen Nov 14, 2025 · Last updated May 21, 2026 · Updated 28 times
Summary
This early-stage study tested a new type of HIV vaccine in 46 healthy adults without HIV. The vaccine uses synthetic DNA to train the immune system, with some participants also receiving a protein boost. The main goal was to check safety and see if the vaccine triggers a strong immune response against HIV.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alabama CRS (Site ID: 31788)
Birmingham, Alabama, 35294, United States
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Bridge HIV CRS
San Francisco, California, 94102, United States
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Brigham and Women's Hospital Vaccine CRS [30007]
Boston, Massachusetts, 02115, United States
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CAPRISA eThekwini CRS
Durban, KwaZulu-Natal, 4013, South Africa
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Durban Adult HIV CRS
Durban, KwaZulu-Natal, South Africa
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Groote Schuur HIV CRS (Site ID: 31708)
Cape Town, Western Cape, 7925, South Africa
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San Francisco Vaccine and Prevention CRS
San Francisco, California, 94102, United States
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Soweto HVTN CRS
Johannesburg, Gauteng, South Africa
Conditions
Explore the condition pages connected to this study.