Can friends help find hidden HIV? new trial recruits peers to boost testing
NCT ID NCT06857071
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests a method where people newly diagnosed with HIV are asked to recruit anyone they know who might benefit from HIV testing. The goal is to find more undiagnosed cases, especially among men who often avoid testing due to stigma. About 2,480 participants from 32 clinics in South Africa will take part, comparing this approach to standard testing.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Expanded Social Network Recruitment to HIV Testing (E-SNRHT) intervention
- What this could lead to
- If successful, this approach could help find more undiagnosed HIV cases and encourage more men to get tested, improving public health efforts.
- What could go wrong
- This is a behavioral study, not a drug trial, so results depend on social factors and may not work in other settings. Stigma and participation rates could limit effectiveness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 2,480 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
"Seeds" (i.e., initial participants in both study arms) will be recruited via referrals from clinics' standard of care HIV testing. To be eligible, seeds must have received a new HIV diagnosis from a study clinic in the last 2 months (i.e., they must be newly diagnosed with HIV infection \[NDH\]), and must have been given a study recruitment coupon by staff at one of these clinics. They will also be screened to ensure that they meet the following additional eligibility criteria: are ≥ 18 years old, are able to be interviewed in English or isiZulu (since over 95% of the population in the Msunduzi region speaks one or both of these languages), are able to give informed consent, and indicate that they reside in the Msunduzi region of KwaZulu-Natal, South Africa. Seeds in the intervention arm (i.e., recruited from intervention condition-assigned clinics) will be asked to recruit their expanded social network members who they think would benefit from testing for HIV. Network members will be eligible to participate if they have a recruitment coupon given to them by a study participant (i.e., if they were recruited by an intervention arm participant); are ≥ 18 years old; able to be interviewed in English or isiZulu; able to give informed consent; and reside in the Msunduzi region. Inclusion Criteria: * Has study recruitment coupon (from clinic or from intervention arm participant) * Is ≥ 18 years old * Is able to be interviewed in English or isiZulu * Is able to give informed consent * Resides in the Msunduzi region Exclusion Criteria: * Does not have study recruitment coupon (from clinic or from intervention arm participant) * Is \< 18 years old * Is not able to be interviewed in English or isiZulu * Is not able to give informed consent * Does not reside in the Msunduzi region
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centre for Community-based Research, Human Sciences Research Council
RECRUITINGPietermaritzburg, KwaZulu-Natal, 3201, South Africa
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