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Twice-Yearly shot could replace daily HIV prevention pills

NCT ID NCT06101329

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 36 times

Summary

This study looks at a new HIV prevention option for cisgender women in the US: a shot given under the skin every 6 months, called lenacapavir. Researchers want to see how the drug behaves in the body, how safe it is, and if women find it acceptable compared to taking a daily pill. About 253 women who have had condomless sex with a man in the past year are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cornell Clinical Trials Unit, New York Presbyterian Hospital - Weill Cornell Medicine

    New York, New York, 10010, United States

  • Fenway Health

    Boston, Massachusetts, 02215, United States

  • George Washington University Medical Faculty Associates

    Washington D.C., District of Columbia, 20037, United States

  • Harlem Prevention Center CRS

    New York, New York, 10027, United States

  • ICAP at Columbia University - Bronx Prevention Center

    The Bronx, New York, 10451, United States

  • NC TraCS Institute - CTRC; University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • Penn Prevention Research Unit

    Philadelphia, Pennsylvania, 19104, United States

  • Ponce de Leon Center Clinical Research Site

    Atlanta, Georgia, 30303, United States

  • Rutgers New Jesey Medical School - Clinical Research Center

    Newark, New Jersey, 07103, United States

  • UAB, 1917 Research Clinic

    Birmingham, Alabama, 35222, United States

  • UCSD Antiviral Research Center (AVRC)

    San Diego, California, 92103, United States

Conditions

Explore the condition pages connected to this study.