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Partners in prevention: couples program boosts HIV protection for women

NCT ID NCT07574619

Prevention Sponsor: RTI International Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a program called CUPID that helps couples make decisions together about HIV prevention. About 1,424 women in Uganda will join with their male partners to choose and use PrEP (medicines that prevent HIV). The goal is to see if partner support increases women's use of PrEP and makes the program easy to use in local clinics.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 1,424 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: All Aims: 1. Able and willing to provide written informed consent 2. Fluent in English or the dominant language spoken in the health facility's region. Aim 1: 1. Age ≥18 years 2. Meets one of the following criteria: 1. Performs tasks related to PrEP outreach and/or delivery in former CATALYST study areas. This may include clinic and non-clinic positions. 2. Is a member of one of the three regional CATALYST CABs 3. Willing to participate in a focus group discussion Aim 2: 1. Aged 18 years or older 2. Attending a PrEP follow-up visit 3. Able and willing to complete all study procedures. Aim 3: 1. Age ≥18 years 2. Meets one of the following criteria: 1. CUPID couples' decision tool user 2. A CUPID intervention provider (member of a CHT or other PrEP Provider) 3. A provider offering PrEP choice through a health facility where CUPID is implemented 4. MOH or District Health Official 3. Willing to complete a questionnaire and participate in a qualitative interview (individual or dyadic) Exclusion Criteria: All Aims: Participants will be excluded who have any condition that, in the opinion of the MPI or designee, would preclude informed consent, make study participation unsafe, complicate interpretation of study outcome data, or otherwise interfere with achieving the study objectives. Aim 2: Exclusion criteria: Participants aged 15-17 years

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Conditions

The condition(s) this trial relates to.

HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Makerere University-Johns Hopkins University Research Collaboration MU-JHU Care

    RECRUITING

    Kampala, Uganda

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