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HIV and the aging brain: a Long-Term look

NCT ID NCT05678660

First seen Jun 02, 2026 · Last updated Jun 06, 2026 · Updated 2 times

Summary

This study follows 298 older adults with HIV to see how the length of time they've had the virus affects their brain health, thinking skills, and physical frailty. Participants are split into two groups: those on HIV treatment for 1-2 years and those on treatment for 7+ years. Researchers will track memory, mental health, and body changes over 6 years to learn more about aging with HIV.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Chikankata Hospital

    Mazabuka, Southern Province, Zambia

  • Chilenje Level 1 Hospital

    Lusaka, Zambia

  • Monze Mission Hospital

    Monze, Southern Province, Zambia

Conditions

The condition(s) this trial relates to.

Aging, Premature Cognitive Dysfunction Frailty HIV infectious disease Psychological Well-Being

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.