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Can two antibodies plus an immune booster keep HIV in check? new study explores a pill-free option.

NCT ID NCT05245292

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 24 times

Summary

This study tested whether a single infusion of two long-acting antibodies (3BNC117-LS and 10-1074-LS) plus repeated doses of an immune-stimulating drug (N-803) can safely control HIV in people who temporarily stop their daily antiretroviral therapy. 28 adults with well-controlled HIV took part. The goal was to see if this combination could delay or prevent the virus from rebounding, potentially offering a treatment-free period.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Perelman School of Medicine University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • The Rockefeller University

    New York, New York, 10065, United States

  • Weill Cornell Medicine, Cornell Clinical Trials Unit

    New York, New York, 10021, United States

Conditions

Explore the condition pages connected to this study.